She was answering a question about whether she believes Trump is racist for calling her “Pocahontas” in reference to Warren once highlighting her Native-American heritage despite there being no record of it.
"Is that calling him a name too?" Muir asked Warren.
"No, it's the fact," she responded, before turning the focus to Trump’s treatment of Gonzalo Curiel, the judge presiding over a number of lawsuits concerning Trump University.
"Come on, look at what he has said about Mexicans, look at what he has said about Muslims. Look at what he has said over and over -- in fact, you don't even have to quote me on this -- when he had ruling against him on Trump University, he was being sued for fraud over that university. He tried to attack the judge, the federal judge in his case."
She added: "Trump said, 'Well, I heard he's Mexican and therefore he can't sit in judgment in my case.' He believed that his bigotry disqualified a Mexican-American judge."
Warren went on to accuse Trump and the Republican Party of increasing "racial bigotry, religious bigotry, attacks on women, attacks on gays, [and] attacks on immigrants."
"That is the heart and the energy of what Donald Trump is bringing to America today," she said.