Clinton, who plans to arrive Monday in the Granite State for two days of events, was a ripe target for the GOP hopefuls -- a few who have already jumped into 2016 presidential race and others who appear to be getting ready to run.
Here's a look at some of the sharpest attack lines -- and laugh lines -- aimed at Clinton as she prepares to begin her second full week as a presidential candidate:
Florida Sen. Marco Rubio:
"Hillary's going to raise $2.5 billion -- that's a lot of Chipotle, my friends."
New Jersey Gov. Chris Christie:
"How would I contrast my style with Hillary's? Listen. We're different people of different generations and so you know we're going to approach things in different ways."
Former Texas Gov. Rick Perry:
"The orchestrator of these policies that we have seen that I just mentioned will most likely be the Democrat nominee for president. She's the one that literally brought the reset button to the Kremlin, to reestablish those new relationships with Russia. Well they did re-set us -- that's for sure -- they re-set us back to pre-1989 from my perspective."
Louisiana Gov. Bobby Jindal:
"We need to contrast with Secretary Clinton on substance. I think it's a mistake for the Democratic Party to engage in a coronation. I think a primary competition would be better for them, but they don't look to me for advice, so that's O.K."
Kentucky Sen. Rand Paul:
"I think that her dereliction of duty, her not doing her job, her not providing security for our forces, for our diplomats, should forever preclude her from holding higher office."
Former Hewlett-Packard CEO Carly Fiorina:
"Hillary Clinton must not be president of the United States. I was asked this morning on Fox News whether a woman's hormones prevented her from serving in the Oval Office -- not that we have seen examples ever of a man's judgment being clouded by hormones, including in the Oval Office. Hillary Clinton cannot be president of the United States, but not because she is a woman. Hillary Clinton must not be president of the United States because she does not have a track record of accomplishment, because she lacks the candor and the transparency that are so necessary to leadership and because she will pursue a set of policies that crush the possibilities and the potential of this great nation."
Real estate mogul Donald Trump:
"You can't just sit down with three people that have been vetted and say, 'oh gee it was a wonderful day' and look nice in a brand new suit that looks like it was from central casting. You just can't do that. Eventually she's going to have to answer questions. She's going to have to answer how she did as secretary of state, OK? I mean the world blew up."
South Carolina Sen. Lindsey Graham:
"I think it's something out of the North Korean playbook. I mean at the end of the day, the dear leader -- Kim Jong-un -- everybody he meets likes him. I can't believe that this is a listening tour. I mean one -- the only way you can listen to her is chase her car down the interstate. You've got to come and do what we're doing here today: Take questions from real live people. And, at the end of the day, if this is a listening tour then I'm going to get drafted by the NBA."
Former Gov. Mike Huckabee:
"Every time I ever ran for public office. I ran against the Clinton political machine. I ran against their money. I ran against them. Virtually every election Bill and Hillary Clinton would come back and campaign against me. If somebody wants to know what it's like running against their organization and their apparatus, come see me and I'll tell you. I'll show you some scars, because I have a few."
Texas Sen. Ted Cruz:
"As I was coming up, I was a little bit startled because I could have sworn that I saw Hillary's Scooby Doo van outside. And then I realized it couldn't possibly be that because I'm pretty sure you all don't have any foreign nations paying speakers right? We want something new. We want new leadership to change the page and to turn around. You know the Democratic version of this I'm pretty sure is Hillary Clinton having a conversation with a Chipotle clerk."