"I hope you know how grateful I am to all of you," Biden said.
Democrats kicked off their convention Monday with a who's who of guests who all touted Vice President Kamala Harris' run for the White House.
Several topics came up during the night including the future of reproductive rights and Project 2025.
Harris made a surprise appearance after several Democratic VIPS took the stage, including Rep. Alexandria Ocasio-Cortez.
The main stars of the night were some of the Democrats' longstanding figures including Secretary of State Hillary Clinton.
But the main spotlight came as President Joe Biden spoke to the cheering crowd, reflecting on his four years as president and his decision to "pass the torch" to Harris.
Peggy Flanagan, Minnesota's lieutenant governor, introduced Rep. Maxine Waters to speak at the DNC. Waters received a standing ovation before speaking.
Flanagan is poised to serve as Minnesota's next governor if Gov. Tim Walz steps down to serve as vice president.
As a citizen of the White Earth Band of Ojibwe, Flanagan would be the first Native American female governor.
DNC Chair Jamie Harrison took the stage to tout the Democrats' work over the last four years and the goals of a Harris-Walz administration.
"The fight continues, and there is still more work to do," he said.
"I know that when we elect Kamala Harris and Tim Walz, they will build on our accomplishments and they will create a country that works for every American," he added.
Harrison encouraged voters to be active in the coming weeks for all races down the ticket.
"In my beloved home state of South Carolina, our motto is, 'While I breathe, I hope.' Folks, I believe in the power of hope, but it's going to take more than hope to win this election," he said.
Delegates and other attendees here in the United Center are amped up -- and have been paying attention.
Chicago Mayor Brandon Johnson got a rousing applause when he said his daughter will be able to see herself in Harris. And when Democratic National Committee Chair Jamie Harrison started off with one of Harris' marquee remarks, the crowd quickly finished it with him.
"When we fight…" Harrison said.
"We win!" the crowd erupted.
-ABC News' Tal Axelrod
Three vulnerable Senate Democrats will sit out the DNC this week: Sens. Jacky Rosen, D-Nev., Jon Tester, D-Mont., and Sherrod Brown, D-Ohio.
A spokesperson from Rosen's campaign said she's choosing to focus on her own reelection this week and will meet with Nevada voters instead. She did, however, join Harris and Walz at a campaign event in Las Vegas earlier this month.
"Senator Rosen supports the Harris-Walz ticket and was glad to join them on the campaign trail in Las Vegas this past weekend," a spokesperson for her campaign said.
A spokesperson for the Tester campaign similarly confirmed he won't be in attendance this week.
Notably, he'll be attending a Pearl Jam concert in Montana this week, with an associated fundraiser for his campaign with the band's bassist the day before. He'll spend the rest of his August farming and meeting with voters face to face, per his campaign.
A spokesperson for Brown also confirmed he won't be in attendance at the convention. A campaign spokesperson did not respond to multiple emails asking for further information about where the senator will be this week.
-ABC News' Allison Pecorin
