Best Social Media Reactions to Peyton Manning's Touchdown Record

LeBron James, Elizabeth Banks and Frank Caliendo weigh in on QB's milestone.

— -- Soak it in, Peyton Manning.

The Denver Broncos quarterback set an NFL record Sunday by throwing his 509th career touchdown pass, breaking the record set by Brett Favre.

The milestone was celebrated on social media, with #Peyton509 becoming a trending topic on Twitter. Manning’s record serves as a chance to look back at his 16 seasons playing with the Indianapolis Colts and, later, the Broncos.

The scene of the record-setting pass.

Following the touchdown, Manning's Broncos teammates celebrated.

They also played keep-away.

The occasion was a chance to poke some fun at Manning.

The ball used in the touchdown is headed to the Pro Football Hall of Fame.

Sunday was Manning's night.

With the touchdown, Manning cements his place in NFL history.

Athletes such as LeBron James, Emmitt Smith and Kevin Durant reflected on the accomplishment.

Celebrities such as Frank Caliendo and Elizabeth Banks celebrated the new record-holder.

Of course, Justin Timberlake got in the final word.