Tyrod Taylor (knee), Sammy Watkins (ankle) out for Bills

— -- HERTFORDSHIRE, England -- Tyrod Taylor will not play for the Buffalo Bills in Sunday's game against the Jacksonville Jaguars in London after doctors determined that Taylor's injured left knee needs more time to heal.

Bills coach Rex Ryan also confirmed Thursday that wide receivers Sammy Watkins (ankle) and Percy Harvin (non-injury related), as well as defensive tackle Kyle Williams (knee), running back Karlos Williams (concussion) and offensive tackle Seantrel Henderson (concussion), will not play in Sunday's game. Watkins was the only player among that group to travel with the Bills to London this week.

Taylor did not practice Thursday after being limited in Wednesday's practice.

"He did a nice job [Wednesday]. We split the reps with [EJ Manuel]," Ryan said Thursday. "But as we came back in the evening, our medical people, our doctors, were looking at him. He still has some soreness in that knee.

"And so that means basically when you touch it and it's still sore, that it hasn't healed all the way. So we're not gonna force this young man out there, put him out there, when he's really not 100 percent."

Taylor was not stepping into his throws early in Wednesday's practice, Ryan added.

"I thought as the practice went on that he looked better to me," Ryan said. "But clearly he wasn't at 100 percent when we run him and things like that."

Manuel will start again for the Bills after completing 28 of 42 passes for 263 yards, one touchdown, one interception and a 81.7 QB rating for the Bills in last Sunday's 34-21 loss to the Cincinnati Bengals.

"He missed a couple of throws, missed a couple of reads, but [he needs to] just keep working," Ryan said Thursday. "Try our best just to be accurate and all that. Stay with the fundamentals and things.

"I think we threw so much last week that some of that, he reverted back a little bit. Turned the ball instead of staying with his fundamentals. He'd been doing a great job of that. So really hone in on that and go out and play. I think he'll do well."

Jaguars quarterbacks coach Nate Hackett and offensive line coach Doug Marrone coached Manuel with the Bills the two previous seasons.