Manslaughter and third-degree murder charges have been filed against Derek Chauvin, the officer who prosecutors say held his knee on Floyd's neck for nearly nine minutes.
Chauvin and the other three officers at the scene have been fired. The Department of Justice is investigating.
Tuesday's biggest developments:
Here is how the news unfolded on Tuesday. All times Eastern.
10:39 p.m.: Trump objects to GOP criticism of church photo op
President Donald Trump lashed out at fellow Republicans who have criticized his decision to clear protesters out of Lafayette Park Monday evening prior to a photo op in front of St. John's Episcopal Church.
He called out Sens. Susan Collins of Maine, James Lankford of Oklahoma and Ben Sasse of Nebraska, who were all critical of the violent removal of peaceful protesters with flashbangs and smoke canisters.
"You got it wrong! If the protesters were so peaceful, why did they light the Church on fire the night before?" he tweeted, though it was a different group of protesters and Monday's group had not been violent. "People liked my walk to this historic place of worship! Sen. Susan Collins, Sen. James Lankford, Sen. Ben Sasse."
8:58 p.m.: Police close Soho to New York Protesters
Police blocked streets in Soho just after New York's 8 p.m. curfew started.
Several boutique stores in the expensive Manhattan neighborhood were damaged by protesters over the weekend. Sidewalks were taped off and barricades were placed in the street preventing anyone from entering.
Even though the curfew banned nonessential workers from being outside, some protesters continued to march throughout the city.
Mayor Bill de Blasio told the radio station 1010 WINS that he ordered Uber and Lyft drivers to no take hails during the early parts of the curfew, because they were used during previous looting.
"Series of tactical moves were made to disrupt the pattern that we saw in the last 48 hours," he said.
8:00 p.m.: Boston protesters hold die-in at Franklin Park
Thousands of protesters rallied peacefully in Boston with a massive "die-in" demonstration in Franklin Park.
The crowds laid on the ground for eight minutes and 46 seconds, the exact time former officer Derek Chauvin placed his knee on George Floyd's neck.
The protesters stayed in the park for at least two hours.
"The peaceful protest at Franklin Park has come to a conclusion. As participants vacate the area, we respectfully remind individuals to remain committed to peace," the Boston police said.
Later in the evening, smoke and multiple apparent fireworks were seen in the air after police called protesters to clear the area. Officers launched pepper spray and tear gas.
7:10 p.m.: DC protests rally behind gate near White House
As Washington, D.C., approached its 7 p.m. curfew, thousands of protesters once again gathered outside the White House.
A chain-link fence was set up just outside the section where officers fired flash bang grenades and tear gas into the crowd 24 hours earlier. The crowd shouted at police officers on the other side but remained peaceful, with some taking a knee.
When some protesters climbed street lights, others in the crowd screamed for them to climb down.
National Guard troops were still deployed in the city, including a group that was lined up on the steps of the Lincoln Memorial.
Sen. Elizabeth Warren, and her husband Bruce Mann, were among the protesters. The former Democratic presidential candidate and her spouse were wearing face masks and interacted with the crowd.
When one protester asked the senator why the president was deploying troops in the city, Warren responded, "Because he's wrong, he's imposing violence on our people. People are here to protest peacefully."
7:05 p.m.: Minneapolis school board votes to cut ties with police
In a unanimous decision, Minneapolis school board members voted Tuesday night to terminate its contract with the Minneapolis Police Department following its actions in Floyd's death.
The school superintendent's office will devise an alternative plan to serve its students, according to the board.
6:47 p.m.: Dr. Birx calls on mayors to test all protesters for coronavirus
Dr. Deborah Birx, the White House coordinator for its coronavirus task force, said during a video appearance at The German Marshall Fund's Brussels Forum that she worries about the spread of COVID among protesters around the country.
Birx said she is particularly concerned with footage that shows many of the protesters not wearing face coverings and with the possible spread to elderly persons.
"And so we're really trying to do the work with mayors to expand testing availability over the next week or two so that the individuals who were involved in the peaceful protest can get tested," she said.
6:38 p.m.: New York protesters take knee outside mayor's mansion
Hundreds of protesters in Manhattan marched to Gracie Mansion, Mayor Bill de Blasio's residence, and took a knee.
The protest was largely peaceful and there were even volunteers giving out face masks and hand sanitizer. Afterward, the crowd made its way to Central Park, according to eyewitnesses.
Across the city protesters continued to hit the streets and remained largely peaceful.
New York's curfew is slated to go into effect at 8 p.m. Uber and Lyft drivers were informed that they won't be allowed to operator between 8 p.m. and 12:30 a.m., according to WABC. Yellow and green cabs would be allowed to operate overnight for essential workers, the city's Office of Emergency Management said.
6:12 p.m.: George Floyd's daughter, girl's mother make 1st public appearance
Gianna Floyd, the 6-year-old daughter of George Floyd, and her mother, Roxie Washington, made their first public appearance since his death at a news conference Minneapolis City Hall.
Washington held back tears as she talked about Floyd and lamented that their child won't grow up with him in her life.
"If there's a problem and she needs her dad, she does not have that anymore," she said.
Floyd moved from Houston to Minneapolis for better job opportunities and to provide for his family, Washington said.
"I want justice for him. Because he was good," she said.
"And this is the proof that he was a good man," Washington said, referring to Gianna.
5:47 p.m.: Denver cop fired over social media post
The Denver Police Department said it has fired an officer and begun an internal affairs investigation after he posted an inappropriate photo on social media while policing the city's protests.
Officer Thomas McClay posted a picture of himself and two other officers in riot gear with the caption, "Let's start a riot," on Instagram, according to the department. The post was taken down, however, police officials said it violated the department's social media policy and was "inconsistent with the values of the department."
5:27 p.m.: Florida police place cop who put knee on back of black suspect on leave
The Sarasota, Florida, Police Department said an officer who was videotaped putting their knee on a black suspect during an arrest last month has been placed on administrative leave pending an investigation.
A video of the unnamed officer putting their knee on Patrick Qwashawn Carroll's neck was put on social media Monday and tagged the department. Police Chief Bernadette DiPino reviewed the video and other footage of the May 18 arrest, immediately initiated a formal internal affairs investigation and placed the officer on administrative leave, according to the department.
"Chief DiPino was disturbed to see an Officer kneeling on the head and neck of an individual in the video. While it appears the Officer eventually moves his leg to the individual's back, this tactic is not taught, used or advocated by our agency," the department said in a statement.
According to the Sarasota Police Department, Carroll, 27, did not require medical attention and did not complain of injuries. He was later charged with possession of ammunition by a convicted felon, resisting arrest and domestic violence
The police are asking anyone who had more information or footage of the arrest to contact them.
Minneapolis police officer Derek Chauvin placed his knee on George Floyd's neck before he died.
5:07 p.m.: St. Paul man charged with shooting at cops during protest
A St. Paul man has been arrested and charged with attempted murder for allegedly firing at officers during Saturday night's protest in Minneapolis, Hennepin County Attorney Mike Freeman announced.
Jaleel Stallings, 27, allegedly stepped out from behind a pickup truck on 14th Avenue South around 10:55 p.m., approached a police SWAT team and "crouched by the driver's side door as if to pick something up, and officers became concerned that debris or rocks were going to be thrown at them," according to the criminal complaint.
The officers fired a non-lethal bullet at Stallings and he opened fire at them in return, the complaint said. Stallings allegedly ran away, but the officers caught up and arrested him, according to the complaint.
He fired "three to four" shots, but all narrowly missed the officers, Freeman said.
An AK-47 style Mini Draco pistol was allegedly found near the right bumper of the truck, according to the complaint.
Stallings is scheduled to make his first court appearance Wednesday and prosecutors are seeking $500,000 in bail, Freeman's office said.
Two other men who were with Stallings were arrested and their charges are pending.
4:30 p.m.: Floyd's family joins protesters at march in Houston
In George Floyd's hometown of Houston, his family joined thousands of protesters in a march Tuesday afternoon.
Before the march began, people silently kneeled for 30 seconds in honor of Floyd, the Houston Chronicle reported.
Demonstrators held up signs with messages including: "black lives matter," "no justice no peace," "white people wake up."
As many as 60,000 people were expected to participate, reported ABC Houston station KTRK.
Harris County Sheriff Ed Gonzalez said he'd be among those attending to show his support.
Houston Mayor Sylvester Turner tweeted Tuesday, "I am praying that today will be uplifting and encouraging for #GeorgeFloyd family, our City and the country as a whole. And I pray those of us in positions of power who have taken the oath to serve will hear the message of those who have marched and commit to justice for ALL."
At one point, a protester hugged Houston Police Chief Art Acevedo.
The march will end with a rally at City Hall.
4 p.m.: French protesters set fires, clash with police
Demonstrations in support of George Floyd are ongoing overseas, including in the French cities of Paris and Lyon.
Protesters there are setting fires and clashing with police officers, who are responding with tear gas.
The French are not only showing solidarity with George Floyd, but also the family of a French black man who died after being arrested by police in 2016.
3:22 p.m.: Minnesota Dept. of Human Rights to investigate police department
Minnesota's Department of Human Rights is launching an investigation into the Minneapolis Police Department after filing a civil rights charge related to Floyd's death, Gov. Tim Walz announced Tuesday.
The investigation will examine the "policies, procedures, and practices over the past 10 years" to determine if the police department "has engaged in systemic discriminatory practices towards people of color," a statement said.
If so, the investigation will work to "ensure any such practices are stopped," the statement said.
Walz called this investigation "only one of many steps to come in our effort to restore trust with those in the community who have been unseen and unheard for far too long."
The Minneapolis City Council issued a statement on Tuesday in support of the civil rights investigation. "We urge the state to use its full weight to hold the Minneapolis Police Department accountable for any and all abuses of power and harms to our community," the council said. The council said it stands "ready to aid in this process as full partners."
As protests spread across the Twin Cities, about 123 people were arrested Monday and early Tuesday, mostly for curfew violations, authorities said. About 13 guns were seized, police said.
A total of 604 people have been arrested since Friday, according to the Minnesota State Patrol, and dozens of fires have been reported in the last several days.
2 p.m.: Floyd Mayweather to pay for George Floyd's funeral
George Floyd's family has accepted an offer from boxer Floyd Mayweather to pay for his funeral, Leonard Ellerbe, the CEO of Mayweather Promotions, told ABC News.
Floyd, who is from Houston, will be laid to rest there on June 9.
1:40 p.m.: NY trooper pushing back demonstrators gets hit by speeding SUV
A 19-year veteran trooper of the New York State Police was pushing back a crowd of demonstrators in Buffalo on Monday night when he was hit by a speeding SUV, authorities said.
A Buffalo police officer was also hit by the car and a second trooper was run over.
Troopers fired at the SUV, state police said, and then the driver and passengers were taken into custody.
The veteran trooper was taken to the hospital with a shattered pelvis and broken leg, state police said. The other officers suffered minor injuries.
Those in the SUV were not seriously hurt.
Two people have been charged.
1 p.m.: Surveillance video released from fatal police shooting in Louisville
Authorities on Tuesday released surveillance video from an incident which caused the death of David McAtee, a black man shot by officers in Louisville, Kentucky, during protests.
McAtee owned a local BBQ restaurant which was frequented by police officers, Mayor Greg Fischer said.
At about 12:15 a.m. Monday, members of the Louisville police and Kentucky National Guard were trying to disperse a crowd when they "were fired upon," Gov. Andy Beshear said. The local police and National Guard returned fire, "resulting in a death," Beshear said.
Video footage from McAtee's restaurant and a neighboring business appeared to show officers approaching McAtee's business, police said Tuesday.
McAtee then appeared to fire a gun outside his restaurant, toward the officers, police said. Officers took cover and returned fire, police said.
From the footage it appears McAtee fired first, police said.
Authorities cautioned Tuesday that the video does not provide all of the answers.
Why officers were approaching McAtee's restaurant in the first place is under investigation, police said.
The officers have not yet been interviewed, police said.
Louisville Metro Police Chief Steve Conrad has since been fired after it was announced that no body camera footage was available of the shooting, The Louisville Courier Journal reported.
Conrad previously said he would retire at the end of June after facing immense pressure following the March death of Breonna Taylor, a young black woman who was shot dead by police while in her home.
The Kentucky State Police will independently investigate McAtee's death, the governor said Monday.
12:15 p.m.: Despite overnight looting, Chicago to move into next phase of reopening
Amid overnight looting, Chicago Mayor Lori Lightfoot promised Tuesday, "we are 110% dedicated to you successfully reopening safely and securely."
Lightfoot said she was with one business owner who "burst into tears" and "broke down" as she looked at the devastation to her store.
Despite the unrest, Lightfoot said Chicago will move into phase 3 of its coronavirus reopening on Wednesday.
"We want economic activity to resume peacefully and safely in every single neighborhood, especially those hurting the most," Lightfoot said.
11:20 a.m.: Nearly 700 arrested in NYC, curfew extended through the week
In New York City, despite an 11 p.m. curfew, nearly 700 people were arrested overnight as peaceful protests devolved into moments of vandalism, looting, fire and confrontation.
Luxury brands and big box retail stores in Rockefeller Center and the Upper East Side had windows smashed and spray painted. Many retailers have boarded up their storefronts.
Some officers were hit by cars of protesters fleeing the scenes of vandalism and looting.
It also appeared officers were shot at, New York City Mayor Bill de Blasio said, condemning it as "unacceptable."
"I know people want peace," de Blasio stressed Tuesday, "and I know they want change."
"I know we will overcome this," he said, adding he's asked community leaders to "step forward" and "take charge."
"Do not let outsiders attack your community ... do not let criminals attack your community," the mayor said. "I'll be standing by you."
De Blasio said he does not think National Guard members should be sent to New York City. They're armed, yet not trained for the city's environment, the mayor said, calling it a "dangerous scenario."
New York City will now be under a nine-hour curfew each night this week, beginning at 8 p.m. and ending at 5 a.m.
The mayor on Tuesday asked those who want to protest to do so during the day, and then return home.
He also said he's very worried that protests are leading to the spread of the coronavirus.
Regular days off have been canceled for all uniformed members of the NYPD, meaning all 36,000 police officers are now working 12-hour shifts, seven days a week until further notice.
10:40 a.m.: Senate Judiciary to hold hearing on George Floyd's death, policing in US
Senate Judiciary Committee Chairman Lindsey Graham said he's planning to hold a hearing on June 16 to examine Floyd's death and policing in the country, promising to "take a deep dive" into the issue.
"It's a long-overdue wake-up call to the country that there are too many of these cases where African American men die in police custody under fairly brutal circumstances," he said. "It's clear to me that policing among men in the African American community is a topic that needs to be discussed and acted upon, and I expect this committee to do its part."
"I'd like to get to the root cause of it. Mr. Floyd's case is outrageous on its face, but I think it speaks to a broader issue," said Graham, R-S.C. "We just need to get to the bottom of what happened and what we can do to fix it."
Graham called community policing "the anecdote."
"I don't know how to make that a reality, but we'll have a hearing along those lines," Graham said.
7:35 a.m.: Minnesota AG 'considering all charges' for Chauvin
Minnesota Attorney General Keith Ellison confirmed he is "considering all charges" and that "all options are on the table," when it comes to prosecuting Derek Chauvin for the death of George Floyd.
Ellison told ABC News' "Good Morning America" that the case must be dealt with methodically and that prosecuting Chauvin would not necessarily be easy.
"Generally, jurors resolve all doubts in favor of the police," said Ellison. "The system is such that there are certain immunities police have, there are certain presumptions. There are relationships that police have that are established over the course of years. And the fact is if you just look at the Freddie Gray case, people looked at that video and were quite certain that there needed to be a conviction. No one was."
"The fact is these cases are not easy," said Ellison. "And anybody who says they are has never done one."
Ellison was reluctant to give a firm deadline on the timeline of the case but confirmed that the public could see charges very soon.
"We are having a fresh review from what the county attorney has already done ... and we are looking at this case with fresh eyes," said Ellison. "There is nobody who has culpability who will not be held accountable."
Said Ellison: "The public has an expectation that there will be, there will render assistance when necessary, that [police] will not add harm. Just saying 'I didn't know' and 'I was following orders', I don't think is working for the public anymore. That is not a comment about the evidence or the law. It is a comment about where the public's mind is these days."
Ellison said that he and his team are moving "expeditiously" but warned that they also have to move carefully which could take more time than the public would like.
"There are numerous videos, numerous witness statements, a lot of stuff to go through for us to do due diligence," Ellison stated. "We are not going to prolong this any longer than is absolutely necessary to do that due diligence and we are moving expeditiously, yet we have to move carefully. I know that is unsatisfying to people. They want, what they want immediately, and of course people have waited too long and have been too patient over the years but this case must be done methodically and we are doing that right now."
6:49 a.m.: Las Vegas police officer in critical condition after shooting
Las Vegas Sheriff Joe Lombardo said two shooting incidents took place amid protests across the city Monday night.
In the first incident, an officer was shot while engaging with protesters near the Circus Circus hotel and casino.
"Our officers were attempting to take rocks and bottles from the crowd," said Lombardo. "Officers were attempting to get some of the protesters in custody when a shot rang out and our officer went down."
The officer is in "extremely critical condition and on life support," he said.
The suspect in that shooting was taken into custody.
The second incident occurred around 11:22 p.m. at the courthouse on South Las Vegas Boulevard. Officers were posted at the federal building to protect it from protesters when a suspect appeared, armed with multiple weapons.
When authorities approached the individual, the suspect reached for one of those weapons and was subsequently shot by the responding officers.
The suspect later died at the hospital.
"This is a tragic night for our community," said Lombardo. "With these protests, which are leading to riots, one tragedy is only leading to another ... our investigations into both these incidents will be ongoing throughout the morning."
"What has occurred is utterly, utterly unacceptable and I hope the community sees it that way too," he concluded.
3:22 a.m.: 4 police officers shot in St. Louis
In St. Louis, four officers were shot amid protests Monday night, Police Chief Hayden John Hayden said.
All four officers have non life threatening injuries. Two were shot in the leg, one was shot in the foot and the other was shot in the arm.
Hayden said that a peaceful protest began around 3 p.m. with a couple of thousand people in attendance, but later a group of about 200 people started looting.
The group reportedly set off fireworks aimed at officers.
Hayden said the officers, who he said exhibited restraint throughout the ordeal, also had gas thrown on them.
That is when, he said, several officers, who were standing on the line, all of a sudden felt pain and realized that they had been fired.
1:57 a.m.: LAPD Chief apologizes for equating looters with officers involved in Floyd's death
In Los Angeles, Police Chief Michel Moore apologized for a remark he made during a mayor's press conference Monday afternoon. He had said: "We didn't have people mourning the death of this man, George Floyd, we had people capitalizing. His death is on their hands as much as it is those officers ... We didn't have protests last night. We had criminal acts."
The comment was met with immediate backlash and Black Lives Matter LA called for Moore to be fired in a tweet.
Several hours later, amid much criticism, Moore issued an apology on Twitter saying that he misspoke during the press conference.
ABC News' Beatrice Peterson, Alexandra Faul, Sabina Ghebremedhin, Will Gretzky, Marilyn Heck, Aaron Katersky, Stephanie Wash, Carlos Gomez, Whitney Lloyd, John Parkinson and Kirit Radia contributed to this report.