Lee County, which encompasses Fort Myers, accounts for most of the fatalities.
The remnants of Ian are charging up the East Coast on Saturday after making landfall as a Category 1 hurricane in South Carolina on Friday afternoon.
The monster storm made its first U.S. landfall on Wednesday on Florida's west coast as a powerful Category 4 hurricane, shredding homes with ferocious winds topping 150 mph. Florida's death toll has climbed to at least 81, according to information from local officials.
Portions of Fort Myers are under up to 4 feet of water, the city said late Wednesday night, and residents are being told to stay inside as first responders try and assess the damage from Hurricane Ian.
"We need to ensure that the roads are clear so that our first responders and our assistance crews can go out there and help everyone that needs us," the city wrote on Twitter. "PLEASE, please, please stay inside."
Jacksonville International Airport has canceled all flights for Thursday and the terminal will be closed.
-ABC News' Ahmad Hemingway
Ian continues to gradually weaken as it moves across the Florida Peninsula, now a Category 1 storm with maximum sustained winds down to 90 mph. The storm is moving to the north-northeast at 8 mph, and the center is currently about 70 miles south of Orlando.
While Ian is weakening, it's still bringing widespread dangerous weather impacts across the state.
-ABC News' Dan Peck
A Flash Flood Emergency has been issued for parts of Sarasota, Manatee, Desoto, Hardee and Highlands counties in west-central Florida, with other areas experiencing life-threatening flash flooding.
Between 12 to 19 inches of rain has already fallen in the area.
-ABC News' Daniel Peck
