Lee County, which encompasses Fort Myers, accounts for most of the fatalities.
The remnants of Ian are charging up the East Coast on Saturday after making landfall as a Category 1 hurricane in South Carolina on Friday afternoon.
The monster storm made its first U.S. landfall on Wednesday on Florida's west coast as a powerful Category 4 hurricane, shredding homes with ferocious winds topping 150 mph. Florida's death toll has climbed to at least 81, according to information from local officials.
A tornado threat is increasing as Hurricane Ian gets closer to the coast of the Carolinas.
Myrtle Beach and Greenville, South Carolina; Wilmington, North Carolina and Virginia Beach, Virginia, are all under tornado watch through 10 p.m.
A tornado warning is also in effect south of Wilmington.
-ABC News' Melissa Griffin
President Joe Biden pledged the U.S. would do "whatever it takes," to help Florida recover from Hurricane Ian, stressing the effort would be done as "one nation and one America," during an event at the White House marking the Jewish New Year.
"We're working very closely with the governor and the entire Florida delegation, Democrat and Republican, making sure that we can do everything we can, including now search and rescue, recovery and rebuilding efforts, but it’s going to go on for a long while. And whatever it takes, we’re going to be there, as one nation, and one America. We're not going to walk away," Biden said.
Biden noted the time of celebration is also a "very difficult time for so many Jewish families in Florida," and those with loved ones in the state.
"[O]ur heart goes out to everyone there in the state experiencing what could be maybe one of the most devastating hurricanes in the history of that state," Biden said.
-ABC News' Molly Nagle
President Joe Biden spoke with South Carolina Gov. Henry McMaster Friday ahead of Hurricane Ian's expected landfall.
Biden told McMaster the administration will provide whatever assistance South Carolina needs. Biden issued an emergency declaration for South Carolina Thursday night.
-ABC News' Molly Nagle
Hurricane Ian is now 60 miles southeast of Charleston, South Carolina, with sustained winds of 85 mph and even higher gusts.
Conditions at landfall, which is expected after 2 p.m., are forecast to be worst in Myrtle Beach. The worst of the storm surge will be from there to the North Carolina border.
More than 4 inches of rain has fallen in South Carolina so far and it is expected to continue.
-ABC News' Max Golembo
