Hurricane Milton live updates: 10 fatalities confirmed

At least 10 fatalities have been confirmed from Hurricane Milton, Secretary of Homeland Security Alejandro Mayorkas said.

"Right now, search and rescue is our highest priority, and we are also praying for those who are unaccounted for and for their safe return," he said.

Mayorkas stressed that, while Milton has gone out to see, the danger is ongoing.

"Downed power lines, floodwaters, non-potable drinking water and debris are creating deadly conditions. Keep listening to local officials and shelter in place until it is safe," he said.

Mayorkas also highlighted the "very significant" number of people who followed guidance to evacuate ahead of landfall, saying the impact of that decision cannot be minimized.

Despite the devastating damage caused by Helene and Milton, Mayorkas said, "We have the capability and the capacity to respond to and recover from multiple simultaneous disasters."

Over 15 million meals and 13 million liters of water have been delivered to the region and another 20 million meals and 40 million liters of water are ready to be deployed, White House press secretary Karine Jean-Pierre said.

"The U.S. Army Corps of Engineers has two temporary power teams and a roofing team to diagnose the need for short term repairs to homes and structures," she said. "The Department of Defense has also provided 60 high water vehicles and personnel who can further aid in search and rescue efforts. To the people of Florida, this is still a very serious situation. Please remain vigilant."

-ABC News’ Justin Ryan Gomez

Five people were killed in the powerful tornadoes that struck St. Lucie County on Florida's east coast, Gov. Ron DeSantis said.

Twelve tornadoes were reported in the county within 90 minutes, prompting over 900 calls to 911, county officials said.

County Administrator George Landry praised the commitment of first responders, saying, "During the storm, our emergency personnel were literally dodging tornadoes to reach residents."

At least 38 tornadoes were reported across Florida on Wednesday. There were 126 tornado warnings issued in South Florida -- the most on record for the state and the second-highest for any state in one day.

-ABC News’ Jason Volack

More than 3.2 million customers are without power in Florida.

More than 50,000 linemen have been pre-staged across Florida to restore power, Gov. Ron DeSantis said.

As Floridians come together to pick up the pieces amid extensive flooding, debris pileup, tornado damage and more, various charities and nonprofits are raising funds and accepting donations to support rescue and relief efforts.

Click here for a list of organizations.