This comes after two weather systems moving through the central U.S. led to snow from Minnesota to Kentucky and created winds of up to 70 mph in Texas, where two people were reported dead.
Cities across the Northeast are already preparing for the coming storm. Mayor Marty Walsh announced Monday afternoon that Boston public schools will be closed Tuesday. He urged businesses to do the same with the city expecting over a foot of snow.
"I encourage Boston's employers to take the weather into consideration tomorrow," Walsh said. "The City offers a number of resources geared towards keeping residents safe and aware of current conditions. I ask each and every single Boston resident to remain vigilant, stay safe and look after their neighbors."
There have already been over 1,150 flight cancellations -- including 765 in Boston -- due to Tuesday's storm. Amtrak announced they will be shutting down Northeast Corridor service between New York City and Boston until at least 11 a.m. on Tuesday.
Monday night, the low is expected to strengthen quickly and snow may break out from coastal New Jersey to New York City out to Long Island, as well as much of eastern New England. Wind gusts may top out around 40 mph.
By late Thursday afternoon, the system is forecast to strengthen rapidly and dump heavy snow on the coastal New England. Boston, Cape Cod and Portland, Maine, could see wind gusts as high as 65 mph and blizzard-like conditions.
Tuesday night into Wednesday morning, the storm will weaken as it moves toward the Canadian Maritimes, leaving behind showers and gusty winds in New England.
Southeastern New England will see the heaviest snowfall, where south of Boston 20 inches could pile up as the city proper sees a foot. New Hampshire, Maine and Connecticut can expect 8 to 12 inches as New York City may get about 2 inches.