Junior linebacker James Hearns and sophomore linebacker Henry Famurewa were shot along with an unidentified Louisville student, sources told WHAS11, an ABC affiliate.
Police were called to an off-campus apartment complex at around 2 a.m. Sunday.
A woman and a man were taken to University Hospital by ambulance due to gunshot wounds while a third person showed up to Jewish Hospital suffering from a gunshot wound, police told WHAS11.
All three are believed to be connected to the incident at the off-campus party where the Heisman celebration was taking place.
Police described their injuries as non-life threatening.
The university sent out two alerts to students. The first came at 4:07 a.m. regarding the shooting, saying Louisville Police officers were on the scene. A second notification was sent at 7:48 a.m. giving the “all clear.”
The university has yet to make an official statement on the incident.
The Louisville Metro Police Department is seeking suspects in the shootings.