The mother of two will invite leading figures in the mental health field to contribute to the issue.
"The Duchess of Cambridge has made the mental health of children a key focus of her work in recent years,” a Kensington Palace spokesman said.
The duchess prepared a public service announcement last year during children's mental health week to shine a light on the issue.
"William and I sincerely believe that early action can prevent problems in childhood from turning into larger ones later in life,” she said in the video message.
Middleton, 34, urged greater action on mental health initiatives in the PSA, saying, "The stigma around mental health means that they do not get the help they so badly need. This needs to change."
The duchess has stepped up her efforts in the mental health arena since returning to work after the birth of Princess Charlotte. And with Prince George now settled in nursery school, she will have more time to devote to her work.