For more than three decades, Gibson has been in more than 40 films.
Gibson said he's not concerned if the audience passes judgment on him.
He said in the Weiner interview that he was "way beyond" what people think and that "the whole experience has been most unfortunate. And so it's not without all the downside."
Gibson said: "I could easily not act again. It's not a problem. I'm going to do something now because I want to do it and because it's fun."
But he does plan to work for "Braveheart" screenwriter Randy Wallace on a project.
In Gibson's latest film, "The Beaver," which is set to open next month, he plays a man who is depressed and uses a puppet in the form of a beaver to talk with his family and his wife.
He told Weiner he found the film to have an "odd quirky humor and at the same time, the very profound undertone of what happens to us and what can happen to us and how do you handle that."
The film features Jodie Foster and the film has received some positive reviews.
The movie explores universal themes like desperation, getting through depression and finding his voice.
Gibson talked about his life now and said he still goes out with his family despite the potential media attention it could attract.
"Yeah, I go out. I do what I need to do. Life goes on. It's part of your job to be out there. But there are aspects that you don't necessarily want and sometimes they are completely unavoidable. You get blindsided and try to deal with it in a pragmatic way," he said in the Weiner interview.
ABC News' Sheila Marikar contributed to this report.