Girl With Flesh-Eating Disease Faces 'Horror,' 'Depression'

May 15, 2012— -- Aimee Copeland, the Georgia student who lost her leg to a rare flesh-eating infection after a zip line injury, is smiling and laughing, according to her family. But the 24-year-old can't remember the events that landed her in critical condition, and faces an extreme psychological adjustment when she does.

"She will learn about the loss of her beautiful leg. She will discover that her hands lack the dexterity and tactile response she has known all her life," Copeland's father, Andy Copeland, wrote in a blog dedicated to his daughter's recovery. "How would you respond in such a situation? I think that moment will be one of horror and depression for Aimee."

Medications designed to keep Copeland calm have blurred her memory of the May 1 accident that cut open her calf, inviting the life-threatening infection that claimed her leg and threatens to take her fingers. But despite her remarkable physical recovery, the psychological wounds of realizing she lost a limb could be harder to heal.

"I want to ask everyone to pray for my child's psyche and for her self-awareness to not be focused on her physical being," Andy Copeland wrote. "Please pray that she will have understanding."

The ventilator pumping oxygen into her lungs makes it impossible to speak. But soon, the breathing tube will be removed, allowing Copeland to ask questions.

"As wonderful as that moment will be for us, it will also be the time that Aimee receives all the answers about her condition," Andy Copeland wrote.

For Copeland, an active and ambitious graduate student, news of the amputation could trigger grief rivaling the physical pain of the infection, according to Dr. Harsh Trivedi, chief-of-staff at Vanderbilt Psychiatric Hospital in Nashville, Tenn.

"For someone who was in good health to be in this situation all of a sudden, that's a pretty substantial loss," he said, alluding to the physical loss of a limb as well as the loss of opportunities in life. "There's almost a grieving process that needs to occur, and that can lead to feelings of depression over how different life is now compared to literally two weeks ago."

Remembering details from the zip line accident also raises the risk of post-traumatic stress disorder, a condition marked by haunting flashbacks, Trivedi said.

But much of how Copeland reacts to the news depends on how it's delivered.

"Some people like to be told flat-out. Some people like to hear a little at a time," Trivedi said, adding that Copeland's questions can help doctors gauge her readiness. "Some people are just happy to be alive."

The bacteria that triggered the infection, Aeromonas hydrophila, thrives in warm climates and fresh water like the river where Copeland was zip lining with friends. The common germ rarely causes flesh-eating disease. But when it does, the infection carries a fatality rate upward of 60 percent, according to 2010 report published in the journal Clinical Microbiology Reviews.

"The words I hear from the medical professionals to describe Aimee's continued recovery are 'astonishing,' 'incredible,' 'confounding,' 'mind boggling' and 'unbelievable,'" wrote Andy Copeland. "All those are fitting words. My favorite word is 'miracle.'"