"I would have a difficult time trusting that jurors with long breaks between hearings and, and evidentiary hearings where they have access to the media, especially in a high profile case, are not reading news accounts," Amador told ABC News.
The first questions will come from her lawyers, but then Knox can be cross-examined by the prosecution, lawyers for the civil plaintiffs and the judge, Giancarlo Massei.
She can choose to interrupt the questioning at any time, or choose to answer certain questions and not others, but if one takes the stand, it is assumed one plans to answer the questions.
Knox's father, who will be in court to support his daughter, says she is eager to take the stand and explains, "Some people may consider [taking the stand] a risk. It's not a risk because she is 100 percent innocent. She knows that and wants to tell the truth."
Amanda Knox's family members says they worry about media portrayal of their daughter as a calculating and conniving killer, dubbed the "angel face with icy blue eyes." For a year and a half, the international press has painted Knox as a person her father says is "180 degrees from who she really is."
He says that with his daughter on the stand, speaking in her own words, "I think people are going to see that she's a real human being, not the monster she has been pictured and painted as."
But not only is Knox up against often harsh and negative press, she also faces the Italian justice system, which has notable differences from the American judicial system.
Deciding Knox's fate are two judges and six jurors. Italian jurors, who, in this trial, are citizens of Perugia, are not screened for biases or preconceived notions perhaps gleaned from the press. They hear testimony on average only two days per week.
It's a dangerous delay for Knox during which the juror's opinion could be swayed by media reports, Black said.
"Letting the jurors read all the press -- the tabloid press has been rough on her," he said.
In Italy, defendants are allowed to and even expected to lie. While witnesses have to swear to tell the truth, defendants do not. It is assumed that if they are defending themselves, they might not tell the whole truth, and will not be charged with perjury if they don't.
To decide a verdict, both the judges and jury vote and only a majority vote is needed. In the United States, a jury vote must be unanimous. Both the defense and prosecution plan to appeal the verdict.
With the court taking nearly a two-month recess for the Italian holiday, a verdict is not expected until the fall. If convicted, Knox and Sollecito face life in prison.
Knox's family refuses to accept the worst case scenario but understand its nightmare will not likely end anytime soon.
Curt Knox reflects in a quivering voice, "We stay focused on Amanda and making sure that that light is there for her. We just work through it, we just have to. We are not going to leave an innocent daughter in a foreign prison."