The lack of African American representation in the South has become even more remarkable in the past decade as the population of blacks in that part of America increased between 2000 and 2010, so that a majority of black Americans now live in the South, according to the most recent Census data.
South Carolina was not one of the 10 states with the highest population of African American residents, which included Georgia, North Carolina, Texas, Maryland, Virginia and Florida.
As a freshman Tea Party representative, Scott said that Congress needed to focus on cutting spending, including in the military.
"In the military budget you have a number of items in there that are Congress' sacred cows," Scott told ABC News' Jon Karl. "The question really is, does it help us to meet our military objectives or does it satisfy our constituents in a way that is inconsistent with the military objective?"
Senate Minority Leader Mitch McConnell released a statement congratulating Scott on his new position, calling it a "historic moment for the Palmetto State."
"As a solid conservative who fights hard for the values and principles he believes in, Tim will help us find real, lasting solutions to the economic challenges facing our nation in the 113th Congress," McConnell wrote Monday.
National Republican Congressional Committee incoming Chairman Greg Walden, R-Ore., said Monday that the NRCC looks forward to working with Scott to "continue leading South Carolina families in the right direction."
"We could not be more proud that Tim Scott's historic career started in the House and that Tim will continue to make history in the Senate. Tim has been an outstanding member of the Republican conference and South Carolina will be well-represented with today's appointment."
Some had suggested comedian and South Carolina native Stephen Colbert might be chasing the Senate seat, but Gov. Haley ruled out that possibility in a Facebook post 10 days ago.
"You forget one thing, my friend. You didn't know our state drink," Haley wrote, linking to a clip of her appearance on Comedy Central's "The Colbert Report," in which Colbert forgot the state drink was milk. "Big, big mistake."