"It was the most frightening thing of my life," she told WGGB of the experience.
"The truck just started shaking and blew right over on its side," Moore said. "My little ... Honda Civic was just shaking and shaking and I thought, 'If this truck is going to be blown over, I'm going to go in the river.'"
Both she and the truck driver survived without major injuries, she said.
Louis Vega hustled diners to the center of the restaurant where he works in Springfield just as the storm blew in.
"No sooner than I ran back in the restaurant and warned everybody the tornado was coming it just hit like that," he said. "Windows started breaking, trees started coming down, roofs started coming off and it's pretty scary."
In Westfield, Mass., downed trees marked the twister's path.
"There's a lot of trees down in Westfield," said Jim Wiggs of Westfield Emergency Management. "We do have a missing part of the roof of a school. There's property damage up in the eastern part of the city. There's some property damage. We're still receiving some reports of trees falling on houses and power lines down throughout the city. It's an absolute, its a mess."
There have been an average of two tornadoes per year in Massachusetts since 1950, though none since 2008, according to the National Oceanic and Atmospheric Administration. The last fatalities from a tornado in the state were in 1995, when three died and 24 were injured by an EF4 tornado.
ABC News' Aaron Katersky, Linsey Davis and Richard Esposito, and ABC News Radio contributed to this report.