Questions do remain. Researchers suspect, for example, that many cases of male infertility have genetic roots, and wonder if children conceived with ICSI will have fertility problems of their own when they reach adulthood. The procedure is expensive as well — $15,000 or more — and the Kilians did not conceive Caroline until the third try.
They say they were lucky their insurance covered almost the entire bill, but not all policies are as generous.
John Kilian says he is still a bit frustrated at the months they lost while his wife was put on fertility drugs, but having a healthy daughter has changed him.
"It changes your outlook when you think about it," he says. Parenthood "is not a given, it's a blessing."
The Kilians have tried ICSI again. They're expecting twins in the fall.