Pitt and Jolie have yet to finalize their divorce but have agreed to handle matters privately for the sake of their six children.
"It's been difficult. I don't enjoy being single," the 42-year-old told the Sunday Telegraph. "It's not something I wanted. There's nothing nice about it. It's just hard. Sometimes maybe it appears I am pulling it all together, but really I am just trying to get through my days."
In addition to the separation from Pitt, Jolie revealed in July that she was recently diagnosed with Bell's palsy.
"Emotionally, it's been a very difficult year, and I have had some other health issues. So my health is something I have to monitor," she told the Telegraph.
"I am so happy I don't have cancer, and that if I do get it, it will be delayed for a few years. The exchange for that peace of mind is quite good," she added. "I think now I need to rediscover a little bit of the old me. I think we lose our way a bit. I have had a lot happen in my life, from certain people passing to health issues to raising the children. And it's been a very good time to absorb and develop and grow."
Pitt and Jolie met in the mid-2000s and after almost a decade together were married in 2014. They have three biological children and three adopted.