"2 planes, 12 best friends, one 30th bday, destination unknown = priceless," she wrote.
We found out real quick what she was up to. "Starting off my 30th year with a roar ?? ... Surrounded by my best friends and all the lions and tigers I can count," she wrote next to a baby cub at a Mexican sanctuary sponsored by the Black Jaguar White Tiger Foundation.
"Gorgeous baby Nicole," she captioned another.
She even posted a picture with her sister, Briana Cuoco, and a piñata. The two celebrated the birthday weekend together.
And it wouldn't be a modern birthday trip without a group pic.
"Serious squad goals ... 12 bffs on the trip of a lifetime!" she wrote next to a pic that included the likes of Ali Fedotowsky and actress Lacey Chabert.