"I'm gonna be honest, he broke me," Griffin said Friday of Trump's response. "I may get arrested today, I don’t know."
The comedian said she is also getting "detailed death threats."
"This is America, you shouldn't have to die" over comedy, she added.
Griffin's First Amendment lawyer, Lisa Bloom, said that the Secret Service reached out to her and that she had to retain a criminal attorney as well. Griffin maintains she was not threatening the president.
Griffin explained that her and photographer Tyler Shields only spent five minutes coming up with the idea and that the pictures were part of a larger photo shoot that didn't include Trump.
The picture was never meant as anything malicious and that it was supposed to be interpreted in different ways, she added.
"I have no desire to threaten him," she said. "I made a horrible mistake and made a horrible call."
When talking about the aftermath of the pictures, Griffin said "I don’t think I have a career after this." She was recently let go from CNN's New Years Eve special and added Friday that at least five concert venues have already canceled some of her shows. The most recent cancellation is her June 17 appearance at Uptown Theatre Napa in Napa, California, which made the announcement on Friday on its Facebook page. No reason was given for the cancellation.
The 56-year-old comedian also spoke about the tweets in response from Trump himself, calling the act "sick" and from the President's wife Melania, which focused on their son Baron's well-being.
"Kathy Griffin should be ashamed of herself. My children, especially my 11 year old son, Barron, are having a hard time with this. Sick!" Trump wrote the morning after the picture started trending on the internet.
Bloom said that Griffin couldn't have imagined that her stunt would be misinterpreted and that other artists have done worse.
"I'm not afraid of Donald Trump ... I'm gonna make fun of him more now," she said Friday.