Stephanie Hathaway, a mother of two, was suffering from postpartum depression after the birth of her second child when she decided to take part in a study for a drug to treat postpartum depression.
“The intrusive thoughts went away and they didn't come back,” Hathaway told “Good Morning America” about the quick relief she felt after taking the drug. “I called my husband and I just remember him saying, ‘I haven’t heard the you in your voice for so long.’”
Zulresso (brexanolone), the new medication from Sage Therapeutics, is expected to be available for use under prescription and strict supervision as early as June.
Women with PPD will get a single, 60-hour intravenous (IV) infusion of Zulresso at a local health care facility, Sage Therapeutics Chief Medical Officer Steve Kanes told ABC News.
Zulresso could cost as much as $20,000 to $35,000 per treatment.
“It was very much like a cloud was lifted and I just remember walking out of the hospital and feeling like me again,” Hathaway told “GMA.”
Hathaway, 33, whose children are now 4 and 2 years old, said she had not even heard of postpartum depression before it happened to her.
“I was unable to make myself cook, unable to make myself clean, very difficult to take care of the baby,” said Hathaway, who also described being plagued by depressing thoughts playing on a loop in her head. “It was just a time of a lot struggle, a lot of hopelessness, and a lot of fear.”
About one in every nine women suffer from postpartum depression in the U.S., according to the Centers for Disease Control and Prevention (CDC).
Women like Hathaway who suffer from PPD have more than just the more common “baby blues.” Symptoms of PPD may include depressed mood, difficulty bonding with your baby, intense anger or anxiety, fear that you’re not a good mother and thoughts of harming yourself or the baby, among other things.
Current treatment can include talk therapy or antidepressants, according to the National Institutes of Health. While a number of antidepressants may be helpful for PPD, they can take weeks to work.
Dr. Jennifer Ashton, ABC News chief medical correspondent and a practicing OBGYN, said the immediate results of the drug Zulresso could be "potentially life-saving." She cited the logistics of the drug, including the cost, as its biggest drawback.
"This isn’t going to be something you can go to your pharmacy to get," Ashton said on "GMA." "[Women] will not be able to breastfeed while they’re actually getting this infusion so they’ll have to pump and dump, as we say."
Of the 130 people who received brexanolone in the Phase III trials, five became excessively drowsy. Two women in the trials had serious adverse events, such as loss of consciousness and passing out, that were treatment related.
Zulresso is different from most antidepressants people use, both in the way it’s administered and in the way that it works. Instead of targeting serotonin, it is a progesterone metabolite that works through the GABA receptors in your brain.
Dr. Ashton answers your questions about Zulresso here:
Linda Drozdowicz, M.D., a fellow in child and adolescent psychiatry at Yale Child Study Center and member of the ABC News Medical Unit, contributed to this report.