Experts Back Switch to New Diabetes Test

June 6, 2009— -- Diabetes experts on Friday urged a switch to a diagnostic test for the disease that's more useful to primary care doctors and more convenient for patients because it doesn't require fasting.

An international panel recommended that a test known as the hemoglobin A1c assay be the new standard test for diabetes. In the past, this test has primarily been used to monitor if diabetes treatment is working. However, the committee -- which unveiled its recommendations at this weekend's American Diabetes Association meeting in New Orleans, La. -- said the A1c test's long-term measurement of chronic blood sugar control problems provides a better diagnosis than current "snapshot" tests.

The test has not been adopted by all doctors for diagnostic purposes. Many of them prefer to rely first on the tried-and-true techniques such as the standard fasting plasma glucose test (FPG) and the less common oral glucose tolerance test -- tests that the A1c screening would unseat as the new standard.

Still, other physicians have welcomed the new screening. Dr. Joel Zonszein, director of the Clinical Diabetes Center at Montefiore Medical Center in New York, said many colleagues have been "waiting years for this to happen."

Proponents favor the A1c because it measures average blood glucose over the preceding two to three months, rather than just at one point in time, the researchers said.

"A1c values vary less than fasting plasma glucose values, and the assay for A1c has technical advantages compared with the glucose assay," said Dr. David M. Nathan of Massachusetts General Hospital, who chaired the expert committee.

"Also, testing for diabetes using A1c is more convenient and easier for patients who will no longer be required to perform a fasting or oral glucose tolerance test," Nathan added.

The recommendations -- made jointly by the American Diabetes Association, the International Diabetes Federation, and the European Association for the Study of Diabetes -- were published online today in Diabetes Care and will appear in the July issue of the journal.