The report also shows that 8,990 laboratory-confirmed influenza-associated hospitalizations were reported across the nation between Oct. 1, 2017 and Jan. 13, 2018.
A total of 110 died during the 2016-17 flu season, but CDC officials said this years flu hasn't even hit its peak.
Among the latest casualties Zainab Momin, a third-grader from Pike Road, Alabama, whose death has yet to be counted in the CDC report.
Ledbetter he's been urging parents to "do the little things that seem inconsequential," such as washing hands, getting the flu vaccine, and making sure sick students stay at home.
"We're working very hard to protect our children," Ledbetter said.
The CDC has identified a particular strain of influenza A, H3N2, as the culprit affecting thousands from coast to coast. Agency officials said 49 of 50 states have reported widespread flu activity at the same time.
In Swampscott, Massachusetts, Phyllis Gotlib, a beloved 68-year-old music teacher at the Clark, Hadley and Stanley elementary school died from flu complications. Schools in the district were closed Friday, so students and staff could attend her funeral.
“Phyllis was a wonderful person loved by everyone. She brought music into the lives of so many children in Swampscott and Marblehead," her family said in statement. "We are shocked and saddened and can’t express how much we will miss her."
In Texas, the influenza outbreak is so severe that the Bonham Independent School District, which has about 2,000 students, canceled classes through Tuesday.
At Loma Linda Medical Center in San Bernardino County, California, the medical staff has erected a triage tent outside the emergency room to handle the influx of flu patients.