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Last Updated: October 21, 2020, 5:01 AM EDT

A pandemic of the novel coronavirus has now killed more than 1 million people worldwide.

Over 38.4 million people across the globe have been diagnosed with COVID-19, the disease caused by the new respiratory virus, according to data compiled by the Center for Systems Science and Engineering at Johns Hopkins University. The criteria for diagnosis -- through clinical means or a lab test -- has varied from country-to-country. Still, the actual numbers are believed to be much higher due to testing shortages, many unreported cases and suspicions that some national governments are hiding or downplaying the scope of their outbreaks.

Since the first cases were detected in China in December, the virus has rapidly spread to every continent except Antarctica.

The United States is the worst-affected country, with more than 7.9 million diagnosed cases and at least 216,639 deaths.

California has the most cases of any U.S. state, with more than 865,000 people diagnosed, according to Johns Hopkins data. California is followed by Texas and Florida, with over 830,000 cases and over 741,000 cases, respectively.

More than 190 vaccine candidates for COVID-19 are being tracked by the World Health Organization, at least 10 of which are in crucial phase three studies. Of those 10 potential vaccines in late-stage trials, there are currently five that will be available in the United States if approved.

Latest headlines:

Here's how the news developed today. All times Eastern.
Oct 14, 2020, 12:39 PM EDT

UK reports nearly 20,000 new cases as new restrictions take force

The United Kingdom registered another 19,724 positive cases of COVID-19 in the past 24 hours, a rise of 2,490 from the day before.

There were also 137 deaths within 28 days of a positive test, down slightly from the previous day's tally of 143.

The cumulative totals now stand at 654,644 positive cases and 57,690 fatalities with COVID-19 on the death certificate, according to the latest data from the U.K. government.

Fresh local restrictions were due to be implemented across swathes of England on Wednesday under a new three-tier system of COVID-19 alert levels, which British Prime Minister Boris Johnson announced on Monday.

The new measures come as England saw its number of infections quadruple in the last three weeks. There are now more patients hospitalized with COVID-19 than when the country went into lockdown in late March, according to Johnson.

Oct 14, 2020, 12:24 PM EDT

White House coronavirus task force briefing shows 26 states in 'red zone'

Twenty-six U.S. states are currently considered in the "red zone" for COVID-19 cases, according to the latest White House coronavirus task force weekly briefing for governors.

Last week's briefing showed 24 states in the red zone for cases, up from 22 states the week prior. The red zone indicates more than 100 new cases per 100,000 population over the past seven days.

The latest briefing, dated Oct. 11, also shows 19 states and Washington, D.C. in the "orange zone," indicating between 51 and 100 new cases per 100,000 population last week.

PHOTO: Nursing assistant Monica Brodsky (left) and nurse Taylor Mathisen work at a drive-thru testing site in the parking lot of the UW Health Administrative Office Building in Middleton, Wisconsin, on Oct. 5, 2020.
Nursing assistant Monica Brodsky (left) and nurse Taylor Mathisen work at a drive-thru testing site in the parking lot of the UW Health Administrative Office Building in Middleton, Wisconsin, on Oct. 5, 2020. A surge of COVID-19 cases in Wisconsin and the Dakotas is forcing a scramble for hospital beds and raising political tensions, as the Upper Midwest and Plains emerge as one of the nation's most troubling hotspots.
Amber Arnold/Wisconsin State Journal via AP

Five states are in the "yellow zone," indicating between 10 and 100 new cases per 100,000 population last week, according to the latest briefing. For weeks, there was only one state -- Vermont -- listed in the green zone, but it has since been moved to the yellow zone.

Some of the states exhibiting particularly concerning trends, as detailed in the briefing, are Wisconsin, Indiana, Idaho, South Dakota, North Dakota and Montana.

ABC News' Josh Margolin and Arielle Mitropoulos contributed to this report.

Oct 14, 2020, 12:19 PM EDT

Analysis shows cases rising in 35 US states plus DC

An ABC News analysis of COVID-19 trends across all 50 U.S. states as well as Washington, D.C. and Puerto Rico found there were increases in newly confirmed cases over the past two weeks in 35 states as well as the nation's capital.

The analysis also found increases in the daily positivity rate of COVID-19 tests in 24 states plus D.C., increases in COVID-19 hospitalizations in 36 states and increases in daily COVID-19 death tolls in 11 states plus Puerto Rico.

The seven-day average of new cases in the United States has now surpassed 51,000, the highest it has been in nearly two months.

Police stand guard outside of a rally with Vice President Mike Pence at Weldall Manufacturing in Waukesha, Wisconsin, on Oct. 13, 2020. The state currently has one of the highest COVID-19 infection rates in the nation.
Scott Olson/Getty Images

Six states -- Iowa, Montana, Oklahoma, South Dakota, Wisconsin and West Virginia -- hit a record number of current COVID-19 hospitalizations in a day. One state -- Wisconsin -- reported its highest single-day increase in the number of new COVID-19 cases and also hit a peak of new deaths from the disease.

The trends were all analyzed from data collected and published by the COVID Tracking Project over the past two weeks, using the linear regression trend line of the seven-day moving average to examine whether a state's key indicators were increasing, decreasing or remained flat.

ABC News' Benjamin Bell, Brian Hartman, Soorin Kim and Arielle Mitropolous contributed to this report.

Oct 14, 2020, 10:28 AM EDT

ICU admissions jump by 13.7% in Italy

The number of patients admitted to intensive care units in Italy has jumped by 13.7% within the past 24 hours, as COVID-19 infections surge again in the country where the pandemic first took hold in Europe.

Italy's civil protection agency confirmed 5,901 new cases of COVID-19 on Tuesday, an increase of 1,282 from the previous day. An additional 41 deaths from COVID-19 were also registered, the country's worst single-day death toll from the disease since June 17.

The cumulative totals now stand at 365,467 cases and 36,246 deaths.

PHOTO: A medical staffer takes swabs as she tests for COVID-19 at a drive-thru testing site at San Paolo Hospital in Milan, Italy, on Oct. 14, 2020.
A medical staffer takes swabs as she tests for COVID-19 at a drive-thru testing site at San Paolo Hospital in Milan, Italy, on Oct. 14, 2020. COVID-19 infections are surging again in northern Italy where the pandemic first took hold in Europe, putting pressure on hospitals and health care workers.
Luca Bruno/AP

Italy, once the epicenter of the coronavirus pandemic, introduced strict new nationwide measures on Tuesday after seeing a sharp uptick in cases in recent weeks.

The European country had gradually loosened restrictions during the spring and summer, following a nearly three-month lockdown that helped get its COVID-19 outbreak under control.

ABC News' Phoebe Natanson contributed to this report.

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