Coronavirus updates: 84% of California population to go on lockdown Sunday night

New York City will receive 465,525 vaccine doses this month, with the focus on health care workers and nursing home residents first, Mayor Bill de Blasio said.

After that, de Blasio said he wants to prioritize the neighborhoods hardest hit, as well as public housing residents.

The first shipments from Pfizer are expected to arrive as early as Dec. 15 while doses from Moderna, if approved on time, are set to arrive as early as Dec. 22, the mayor said.

New York City’s seven-day positivity rate stands at 5.19%.

-ABC News' Aaron Katersky

An additional 2,804 deaths from COVID-19 were registered nationwide on Wednesday -- the highest recorded death toll on a single day for the U.S., according to a real-time count kept by Johns Hopkins University.

The latest daily death toll shatters the previous record of 2,609 new deaths on April 15, according to Johns Hopkins data.

The nations death toll now stands at 273,590.

There were 200,007 new cases of COVID-19 confirmed in the U.S. on Wednesday, according to Johns Hopkins -- the 30th straight day that the U.S. reported over 100,000 newly diagnosed infections, and only the second time since the start of the pandemic that the figure has exceeded 200,000. Wednesday's count is just under the country's peak of 205,557 new cases recorded last Friday, according to Johns Hopkins data.

Over 13.9 million people in the U.S. have been diagnosed.

Former Presidents Barack Obama, George W. Bush and Bill Clinton have offered to get vaccinated in front of cameras if it will help show Americans they can trust the science.

Bush's chief of staff, Freddy Ford, told CNN, "The vaccines need to be deemed safe and administered to the priority populations. Then, President Bush will get in line for his, and will gladly do so on camera."

Clinton's press secretary, Angel Urena, told CNN on Wednesday, "President Clinton will definitely take a vaccine as soon as available to him, based on the priorities determined by public health officials. And he will do it in a public setting if it will help urge all Americans to do the same."

Obama told SiriusXM host Joe Madison this week, "If Anthony Fauci tells me this vaccine is safe, and can vaccinate, you know, immunize you from getting COVID, absolutely, I'm going to take it."

"I may end up taking it on TV or having it filmed, just so that people know that I trust this science, and what I don't trust is getting COVID," Obama said.

Dr. Anthony Fauci spoke to ABC News Live anchor Linsey Davis Wednesday about the latest developments in the coronavirus vaccine.

The director of the National Institute of Allergy and Infectious Diseases said he was pleasantly surprised at the high efficacy rate of the Moderna and Pfizer vaccines.

"You know, 94% and 95% is almost as good as it gets," he told ABC News Live. "That's almost as good as measles, which is the gold standard of a highly effective vaccine."

10:48

Dr. Fauci on the fight against COVID-19

Dr. Anthony Fauci talks with ABC News’ Linsey Davis about the pandemic during the holidays, the newest Centers for Disease Control and Prevention guidelines and vaccines currently being prepared.

When asked when Americans are likely to see things returning to normal, Fauci said at least 70% of the population would have to be vaccinated.

"If we can do that, we can get a blanket of immunity over this country that as we get into summer and early fall, we could be very close to normal," he said.

Fauci reiterated that Americans need to continue to adhere to health guidelines to slow the spread of the virus over the next couple of months. He again recommended that people curtail travel and avoid crowds during the holidays.

"Any kind of congregate settings where you have large numbers of people indoors particularly without masks is a very risky situation," Fauci said. "It doesn't matter where you are, who you are or where you're doing it -- it's a risky situation."

-ABC News' Haley Yamada