Coronavirus updates: State reports over 49,000 new cases, 468 new deaths

More than 373,000 Americans have died from COVID-19.

Last Updated: January 11, 2021, 7:47 AM EST

A pandemic of the novel coronavirus has now infected more than 90 million people worldwide and killed over 1.9 million of them, according to real-time data compiled by the Center for Systems Science and Engineering at Johns Hopkins University.

Latest headlines:

Here's how the news developed this week. All times Eastern.
Jan 06, 2021, 1:52 PM EST

LA seeing infection every 6 seconds, death every 10 minutes: Mayor

Hard-hit Los Angeles is enduring a new coronavirus infection every six seconds and a new death every 10 minutes, Mayor Eric Garcetti said Wednesday.

Cars line up at the Dodger Stadium COVID-19 testing site, which is the largest in the U.S., on Jan. 4, 2021, in Los Angeles.
Al Seib/Los Angeles Times via Getty Images

The mayor spoke at one of four new vaccination sites opening on Wednesday for health care workers who cannot get vaccinations through employers.

Overall, the city of Los Angeles will be administering over 2,000 vaccinations every day, he said.

 ABC News' Abigail Shalawylo contributed to this report.

Jan 06, 2021, 1:05 PM EST

CDC estimates life-threatening allergic reactions could occur in 11 out of 1 million vaccine shots

The U.S. Centers for Disease Control and Prevention said it estimates that life-threatening allergic reactions could occur in about 11 out of every 1 million COVID-19 vaccine shots given. 

That number is about 10 times higher than anaphylactic reactions to flu shots. However, officials are cautioning that the chances of any kind of adverse reaction are still incredibly rare as well as easy to manage so long as the person has access to treatment such as epinephrine.

“Our vaccine safety systems haven't picked up any worrisome signal. This means that right now, the known and potential benefits of the current COVID-19 vaccine outweigh the known and potential risks, getting COVID-19,” Dr. Nancy Messonier, director of the CDC’s National Center for Immunization and Respiratory Diseases, said Wednesday.

PHOTO: A nurse inoculates former Gov. Jim Hunt and his wife Carolyn with their first dose of the Moderna COVID-19 vaccine at the Wilson County Health Department on  Jan. 6, 2021, in Wilson, N.C.
A nurse inoculates former Gov. Jim Hunt and his wife Carolyn with their first dose of the Moderna COVID-19 vaccine at the Wilson County Health Department on Jan. 6, 2021, in Wilson, N.C.
Robert Willett/The News & Observer via AP

With both the Pfizer and Moderna vaccines available in the U.S., Messonier said one isn’t thought to be more prone to trigger allergies.

The CDC’s estimate is based on 21 cases of anaphylaxis following a 10-day period after the administration of 1.9 million doses of the Pfizer vaccine. The vast majority of these reactions -- 71%-- occurred within 15 minutes of the vaccination. Follow-up information was provided on 20 of the 21 cases, and all of them recovered. 

The CDC recommends that anyone experiencing a life-threatening reaction to the vaccine not receive the second dose.

They also recommend that people with a history of allergies be observed for 30 minutes after receiving the shot.

ABC News' Anne Flaherty contributed to this report.

Jan 06, 2021, 12:35 PM EST

12 US states in South, West report record-high hospitalizations

Approximately 1 in every 15 Americans has contracted the coronavirus, according to ABC News’ analysis of data compiled by the COVID Tracking Project.

Since the beginning of the pandemic, over 700,000 Americans have been hospitalized with the virus.

A patient lies on a hospital bed in a hallway with other patients in the overloaded Emergency Room at Providence St. Mary Medical Center amid a surge in COVID-19 patients in Southern California on Jan. 5, 2021, in Apple Valley, Calif.
Mario Tama/Getty Images

On Tuesday, 12 U.S. states -- mostly in the South -- reported a record number of patients hospitalized: Alabama, Arizona, Arkansas, California, Georgia, Mississippi, North Carolina, South Carolina, Tennessee, Texas, Virginia and West Virginia.

A patient is seen lying on a bed in the COVID-19 intensive care unit on New Year's Day at the United Memorial Medical Center on Jan. 1, 2021, in Houston.
Go Nakamura/Getty Images

Some data may be skewed due to incomplete reporting over the holidays.

ABC News' Arielle Mitropoulos contributed to this report.

Jan 06, 2021, 10:54 AM EST

European Commission authorizes Moderna vaccine

The European Commission granted a conditional marketing authorisation for the Moderna vaccine Wednesday, following the European Medicines Agency’s recommendation.

A person unpacks a special refrigerated box of Moderna Covid-19 at the East Boston Neighborhood Health Center in Boston, Dec. 24, 2020.
Joseph Prezioso/AFP via Getty Images, FILE

European Commission President Ursula von der Leyen said in a statement, "With the Moderna vaccine, the second one now authorised in the EU, we will have a further 160 million doses. And more vaccines will come. Europe has secured up to two billion doses of potential COVID-19 vaccines. We’ll have more than enough safe and effective vaccines for protecting all Europeans.”

ABC News' Christine Theodorou contributed to this report.

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