Moscow saw a 311% month-to-month increase in COVID-19 deaths for October, health authorities said.

According to the Moscow Healthcare Department, the Russian capital reported 543 COVID-19 deaths in September followed by 2,235 deaths in October -- an increase of more than 311% -- as a second wave of the coronavirus pandemic swept the country.

Meanwhile, Russia reported a sharp increase in COVID-19 infections on Friday, with the country's coronavirus response headquarters confirming a record 27,543 new cases in the last 24 hours. An additional 496 new deaths from the disease were also registered nationwide in the past day. The country's cumulative total now stands at 2,215,533 confirmed cases, including 38,558 deaths.

Moscow continues to be the epicenter of Russia's COVID-19 outbreak and recent surge. The city accounted for nearly 29% of the newly reported cases and more than 15% of the newly registered deaths, according to the country's coronavirus response headquarters.

The Eastern European nation of 145 million people has the fifth-highest tally of COVID-19 cases in the world, behind only the United States, India, Brazil and France, according to a real-time count kept by Johns Hopkins University.

ABC News' Alina Lobzina contributed to this report.

There were 110,611 new cases of COVID-19 confirmed in the United States on Thursday, the day of Thanksgiving, according to a real-time count kept by Johns Hopkins University.

It's the 24th straight day that the country has reported over 100,000 newly diagnosed infections. Thursday's count is down from a peak of 196,004 new cases on Nov. 20.

An additional 1,232 fatalities from COVID-19 were also registered nationwide on Thursday, less than the all-time high of 2,609 new deaths on April 15.

COVID-19 data may be skewed this week and next due to possible lags in reporting over Thanksgiving followed by a potentially very large backlog from the holiday.

A total of 12,885,299 people in the United States have been diagnosed with COVID-19 since the pandemic began, and at least 263,462 of them have died, according to Johns Hopkins. The cases include people from all 50 U.S. states, Washington, D.C. and other U.S. territories as well as repatriated citizens.

Much of the country was under lockdown by the end of March as the first wave of pandemic hit. By May 20, all U.S. states had begun lifting stay-at-home orders and other restrictions put in place to curb the spread of the novel coronavirus. The day-to-day increase in the country's cases then hovered around 20,000 for a couple of weeks before shooting back up and crossing 100,000 for the first time on Nov. 4.

The Covid Tracking Project reported 1,319 deaths, below the seven-day average of 1,549, on Thanksgiving, but experts caution against reading too much into data reported before next week as the holiday could prove a catalyst for the virus that's killed at least 263,196 Americans.

On Thursday, total global deaths reached at least 1,428,671.

More than 30,000 people in the United States have died from COVID-19 so far this month, according to an ABC News analysis of data collected and published by the COVID Tracking Project.

Of those deaths, 11,507 were reported in just the last seven days. That's about one American death from COVID-19 reported every minute.

The country's COVID-19 death rate has been steadily rising for the past month. Since Oct. 25, the seven-day average of U.S. daily deaths from the disease has doubled, increasing by 103%.

The increase in deaths follows weeks of surging case numbers across the country. The United States is now reporting an average of over 172,000 new cases of COVID-19 per day.

More than 3.5 million cases were recorded in the month of November so far, including at least 22 straight days where over 100,000 new cases were reported. There were 1.2 million cases reported in the last week alone, which means one in every 271 Americans tested positive for COVID-19.

On Wednesday, two of the country's largest states, California and Texas, both reported their highest single-day case count to date. They are the only two states in the nation to surpass 1 million total cases.

ABC News' Benjamin Bell, Brian Hartman, Soorin Kim and Arielle Mitropoulos contributed to this report.