Updated mask guidance from the CDC is expected to come as early as next week, officials confirmed to ABC News.

CDC Director Dr. Rochelle Walensky did not elaborate on the timing at Wednesday's White House briefing, only saying the CDC could "soon" update its guidance.

“We are looking at all of our guidance based not only on where we are right now in the pandemic, but also on the tools we now have at our disposal -- such as vaccines, boosters, tests and treatments -- and our latest understanding of the disease,” Walensky said. “We want to give people a break from things like mask wearing when these metrics are better and then have the ability to reach for them again should things worsen.” 

Walensky added, "Omicron cases are declining and we are all cautiously optimistic about the trajectory we are on ... but we want to remain vigilant to do all we can so that this trajectory continues."

Walensky also stressed that it is still critical for Americans to continue to wear masks if they are symptomatic, have been recently exposed or if they are 10 days post-COVID-19 diagnosis.

-ABC News' Anne Flaherty,  Arielle Mitropoulos

Forecast models used by the CDC suggest that daily COVID-19 fatalities will finally begin to fall in the U.S. in the weeks to come.

The ensemble model estimates that only eight states have a greater than 50% chance of having more deaths over the next two weeks compared to the past two weeks, and two states and territories have a greater than 75% chance of seeing an increase.

The models predict the U.S. death toll will be at approximately 968,000 by March 12.

The CDC obtains the forecasts from the COVID-19 Forecast Hub at the University of Massachusetts Amherst, where a team monitors and combines forecasting models from the nation’s top researchers. The team then creates an ensemble -- displayed like a hurricane forecast spaghetti plot -- usually with a wide cone of uncertainty.

-ABC News' Arielle Mitropoulos

The U.S. daily case rate has dropped to 144,000 -- an 81% drop since the peak about one month ago, according to federal data.

But experts continue to caution that the pandemic is not over, with the country reporting millions of new cases every week and 97% of counties still reporting high transmission. Experts also point out that many Americans are taking at-home tests and not submitting their results, so case totals may be higher than reported.

Deaths -- a lagging indicator -- remain high.

The U.S. is reporting an average of 2,200 lives lost to COVID-19 each day.

Fifteen states are reporting at least a 10% increase in daily death rates over the last week: Alaska, Alabama, Arizona, California, Delaware, Georgia, Kentucky, North Carolina, New Mexico, Oklahoma, South Dakota, Texas, Utah, Vermont and West Virginia.

-ABC News' Arielle Mitropoulos

A new report from the United Kingdom's public health agency highlights mounting evidence that getting vaccinated can significantly reduce the risk of developing long COVID. 

Most people recover fully from COVID-19 but some experience symptoms like fatigue, shortness of breath and brain fog for months after infection. 

The U.K. report summarizes the results of 15 previously published studies on long COVID from around the world. Collectively, these studies suggest that people who have been vaccinated are far less likely to develop long COVID.

-ABC News' Arielle Mitropoulos, Sony Salzman