About 1,660 of those deaths have been since mid-September.
The Israel Defense Forces continued intense air and ground campaigns against Hezbollah in Lebanon and against Hamas in the Gaza Strip.
The uptick in offensive operations came days after Israel marked the anniversary of Hamas' Oct. 7 assault and as Israeli leaders planned their response to last week's Iranian ballistic missile attack.
At least 22 people were killed overnight in Jabalia in Israeli airstrikes, according to the Gaza Ministry of Health. A total of 42,175 people have now been killed since Oct. 7 last year.
The IDF operation in Jabalia continues on it's seventh day now as Doctors without Borders reports that people trying to evacuate are being shot as the hospital they were working in was bombed.
The Biden administration announced additional sanctions targeting Iran's petroleum and petrochemical production -- areas that are already heavily sanctioned by the West -- in response to Iran’s missile attack on Israel earlier this month.
In response to Iran's "unprecedented" attack, the State Department is "taking steps today to disrupt the flow of revenue the Iranian regime uses to fund its nuclear program and missile development, support terrorist proxies and partners, and perpetuate conflict throughout the Middle East," Secretary of State Antony Blinken said in a statement.
The State Department is imposing sanctions on six entities involved in Iranian petroleum trade and identifying six vessels as blocked property, Blinken said. The Department of Treasury is also sanctioning 10 entities and identifying 17 vessels as blocked property, he said.
Two drones crossed from Lebanon into Israel, the Israel Defense Forces said after sirens sounded in central Israel.
One of the drones was "successfully intercepted," while a building in the Herzliya municipality was damaged, the IDF said. No injuries have been reported so far, it said.
There are power outages in several neighborhoods in Herzliya, a city in the northern Tel Aviv district of Israel that's home to about 100,000 people.
-ABC News' Dorit Long and Clark Bentson
Two Lebanese soldiers were killed in an Israeli strike in Kafra in southern Lebanon, the Lebanese army said in a post on X Friday.
Nearly 60 airstrikes were recorded in various parts of Lebanon over the past 24 hours, largely concentrated in the south, according to a situation report from the Lebanese prime minister's office on Friday.
Sixty people were killed and another 168 injured in the past 24 hours in Lebanon, the Lebanese Ministry of Public Health said Friday. Since the beginning of the increased fighting in mid-September, 2,229 people have been killed and 10,380 others injured, it said.
-ABC News' Ghazi Balkiz
