The IDF says Hamas was using the schools as command centers and hiding places.
As the Israel-Hamas war continues, tensions are escalating after the assassinations of two Hamas and Hezbollah leaders this week.
At least 16 people have been killed in the Israeli strike on the Hamama School, according to the Gaza civil defense.
Israel has claimed that the school was being used as a "command and control" center by Hamas.
The U.S. Central Command Forces said it struck and destroyed one Iranian-backed Houthi land attack cruise missile in Yemen.
"It was determined the LACM presented an imminent threat to U.S. and coalition forces, and merchant vessels in the region. These actions were taken to protect freedom of navigation and make international waters safer and more secure," CENTCOM said in a statement Saturday.
-ABC News' Shannon K. Kingston
The U.S. embassy in Beirut has issued a warning to U.S. citizens in Lebanon "who wish to depart Lebanon to book any ticket available to them." The embassy warned those who choose not to leave to "prepare contingency plans for emergency situations and be prepared to shelter in place for an extended period of time."
"The U.S. Embassy notes several airlines have suspended or cancelled flights, and many flights have sold out; however, commercial transportation options to leave Lebanon remain available. Please see available flight options at Beirut–Rafic Hariri International Airport," the embassy said.
"U.S. citizens who lack funds to return to the United States may contact the embassy for financial assistance via repatriation loans," the embassy said.
At least 10 Palestinians have been killed after the Israeli Defense Forces conducted an airstrike on a school in Gaza City on Saturday, claiming it was being used as a "command and control" center by Hamas.
Gaza civil defense said they are having trouble reaching victims because of continuing bombardment of the school.
