Stephen Allen, USAID's Disaster Assistance Response Team leader for the agency’s earthquake response, said his top priority is getting two American urban search and rescue teams to the region.

"Every hour does count in the first few days,” he said.

The responders are en route to Turkey, where they are expected to land at Incirlik Air Base in Adana Wednesday morning local time, Allen said. They’ll immediately start the long journey to Adıyaman, a city in southeastern Turkey that’s been heavily impacted by the quake, but has not had access to many search and rescue teams, Allen said.

The Americans are bringing about 170,000 pounds of specialized tools and equipment, including hydraulic concrete breaking gear, saws, torches, drills and advanced medical supplies to treat and triage the wounded, he said. They will also have about a dozen dogs who Allen said will play a “very key” role in looking for survivors strapped in the rubble.

Sending search and rescue teams to a disaster site so far away is “not something that we would normally do, frankly,” he said, however Turkey officials asked for assistance because its own considerable national search and rescue capabilities are outmatched by the “size and scale” of the devastation.

“I do need to emphasize the level of devastation, the level of damage, and the expected result in loss of life is massive. It’s massive,” he said.

-ABC News’ Shannon Crawford

Mexican Secretary of Foreign Affairs Marcelo Ebrard tweeted photos and videos of rescue dogs headed from Mexico to Turkey to help with the rescue operations.

The Port of Iskenderun in southern Turkey sustained heavy damage on Monday.

The port, located on the Mediterranean coast in the southern province of Hatay, was damaged due to the earthquake that struck Turkey and neighboring Syria.

"The Port of Iskenderun remains closed until further notice, as teams look to repair the significant damage caused by the disaster and subsequent fire," shipping group AP Moller Maersk said in a statement Tuesday. "We are currently unable to say exactly how long operations will be stopped at the port, but we will keep customers informed of the latest developments as soon as possible."

Maersk said it was not accepting any new bookings to or from the port and were developing contingency plans with nearby hubs.

-ABC News' Will Gretsky

Christian Atsu, a professional soccer player for the Turkish team Hatayspor, was among the more than 8,000 people rescued from the rubble in Turkey, according to his team.

Atsu was injured in the quake. The sporting director for Atsu’s team remains under the rubble, according to a team vice president.

Atsu was on Ghana's 2014 World Cup team and also played for Newcastle United in the English Premier League.

-ABC News’ Will Gretsky