At the 2021 National Prayer Breakfast, lawmakers from both sides of the aisle spoke of unity and oneness under God, and every living former president gave a video contribution to the virtual event -- except former President Donald Trump.
In some ways, Trump's legacy was still present, as Biden focused his remarks on healing the divisions caused by the 45th president.
"We know now we must confront and defeat political extremism, white supremacy and domestic terrorism. For so many in our nation, this is a dark dark time. So where do we turn? Faith," Biden said.
Biden said that while he's attended many prayer breakfasts over the years, "with a nation at war and struggle and strife, and a nation at peace and prosperity," this year was different than any other before, citing the coronavirus pandemic and civil unrest.
"This is not a nation that can or will simply stand by and watch this. It's not who we are. It's not who faith calls us to be. In this moment, we cannot be timid or tired. We have too much work to do. And it's by our work, not just our words, that we're going to be judged," he said.
The devout Catholic ended with his conviction that faith will sustain Americans through the pandemic, citing Psalm 30:5: "weeping may endure for a night, but joy cometh in the morning."
At last year's event, which came right after the Senate voted to acquit his first impeachment charges, Trump held up newspaper headlines reading "Trump acquitted" and took swipes at Sen. Mitt Romney's Mormon faith, as well a House Speaker Nancy Pelosi's penchant for saying she prays for him.
-ABC News' Sarah Kolinovsky