In a statement, McCain said he believes Haspel is a “patriot who loves our country and has devoted her professional life to its service and defense.”
“However,” McCain continued, “Ms. Haspel’s role in overseeing the use of torture by Americans is disturbing. Her refusal to acknowledge torture’s immorality is disqualifying.”
He added: “I believe the Senate should exercise its duty of advice and consent and reject this nomination.”
"Please answer yes or no. Do you believe, in hindsight, that those techniques were immoral?" Harris asked of the nominee.
Haspel responded: "Senator, what I believe sitting here today is that I support the higher moral standard we have decided to hold ourselves..." before Harris cut her off, again pressing her to answer the question.
"I think I've answered the question," Haspel replied.
"No you've not. Do you believe the previous techniques now armed with hindsight, do you believe they were immoral yes or no?" Harris asked.
"Senator, I believe that we should hold ourselves to the moral standard outlined in the army field manual," Haspel replied, not directly answering Harris' question.
Later on in the hearing, Haspel affirmed that should she be confirmed, she will not bring back the agency's controversial rendition, detainee, and interrogation program.
“I can offer you my personal commitment clearly, and without reservation, that under my leadership, on my watch, CIA will not restart a detention and interrogation program. CIA has learned some tough lessons from that experience," Haspel said during the confirmation hearing before the Senate Select Committee on Intelligence.
"We were asked to tackle a mission that fell outside our expertise. For me, there is no better example of implementing lessons learned than what CIA took away from that program,” she said.
Despite McCain's firm rebuke of Haspel, it was not enough to sway his closest ally in the Senate.
ABC News' Luis Martinez contributed to this report.