"To Melania and Don and Ivanka and Eric and Tiffany and Barron, I love you and I thank you, and especially for putting up with all of those hours," Trump said. "This was tough."
After Trump takes the oath of office on January 20, 2017 and officially becomes America's 45th president, his family will likely have prominent roles in public life.
Here's a look at the incoming First Family:
The first lady's role in the White House can vary. Mrs. Trump told the New York Times back in 1999 that her role as first lady would be "very traditional. Like Betty Ford or Jackie Kennedy. I would support him."
In her November 3rd speech this year, Mrs. Trump said that she would focus on women and children's issues and cyber bullying.
"It is never okay when a 12-year-old girl or boy is mocked, bullied or attacked," Melania Trump said. "It is terrible when that happens on the playground and it is unacceptable when it's done by someone with no name hiding on the internet. We have to find a better way to talk to each other, to disagree with each other, to respect each other."
She will also have a role in the White House transition.
"She should expect, through her staff, a lot of questions from the residence staff that's there, over 100 people, that will want to take care of them for the next four years," Anita McBride, former chief of staff for first lady Laura Bush, said in an interview on "GMA" Thursday.
"What the staff is there to do right after the inaugural parade, you walk into the White House, the first time as the new first family, your things are unpacked," McBride said. "Things that you might like to eat are there. The way you're going to entertain your family, who is going to sleep over, all that is decided well ahead of time."
Ivanka Trump, Donald Trump Jr., Eric Trump, and Tiffany Trump
Three of the Trump children, Ivanka, Donald Jr. and Eric, may continue managing The Trump Organization while their father serves as president.
Perhaps the most well-known of Trump's children, Ivanka Trump, the mother of three children, may continue running her fashion business.
However, in an interview, her father didn't rule out a cabinet position for Ivanka.
"I can tell you everybody would say ‘Put Ivanka in!'" Trump said about potential women cabinet members.
Ivanka Trump is married to Jared Kushner, a 35-year-old real estate developer, who had a huge behind-the-scenes hand in Trump's campaign, and may have a role in a Trump administration.
Donald Trump Jr. may also have political ambitions of his own. In an interview with George Stephanopoulos in October, Trump Jr. was asked if he would consider running for office.
"It's a tough process, it's a brutal process, but there is also that element that's just amazing to be able to touch someone that way. And I've seen my father doing that. So I don't know, my only mission is to get him there because I know he can make a difference."
Tiffany Trump, Trump's daughter with his second wife Marla Maples, has also expressed interest in joining the family business.
"I'm applying to law school, though, so I'd like to bring a different kind of skill set to the company," she told Stephanopoulos in October. "But we'll see what happens in the future. But they work so hard and it really, really is inspiring to see."
10-year-old Barron Trump might be the only one of Trump's children to join him in residing in the White House -- if the Trumps chose to live there. There's no requirement that the president has to live in the White House.
A president's young children are usually kept out of the national spotlight, in hopes of giving them a normal childhood in the White House.
"I keep him balanced and just have his childhood as normal as possible. He's enjoying his school and his sports. He's a great athlete. And I just want to have him out of the spotlight for now," Melania Trump told ABC News' George Stephanopoulos in an interview in October.
But Barron's life has been anything but normal. He has his own floor in their three-level Manhattan penthouse apartment, complete with toys such as a red Mercedes toy car.
He currently attends a private school on Manhattan's Upper West Side where yearly tuition is more than $45,000.
Mrs. Trump said in an interview with Parenting.com that she calls Barron "Little Donald," because of their similarities in personality. The sharply dressed 10-year-old also enjoys golfing and building things like his father.
Mrs. Trump also shared that Barron is creative and has a "big imagination."
"In his space the décor style of the rest of our home is mixed with what he is into: planes and helicopters. We let him be creative; let his imagination fly and do whatever he wants," Mrs. Trump said of her only son. "When he was smaller he started drawing on the walls. His imagination is growing and important. He draws on the walls in his playroom, we can paint it over."
Former chief of staff for first lady Laura Bush, Anita McBride added in her "GMA" interview Thursday that Barron can expect a "big change," but he'll still be able to have his friends over and there will be "lots of things there for him to share with his friends, including a movie theater."