The Tennessean earlier reported that the Titans planned on starting Mettenberger.
Locker has missed the past two games with a bruised thumb and another game with a wrist injury.
Coach Ken Whisenhunt had said Locker would throw Tuesday and they would assess how he responds.
Whisenhunt has also said nothing has changed in his thinking about the Titans' quarterbacks, meaning Locker will return as the starter when healthy.
The Titans (2-5) will be looking to avoid a sixth defeat in seven games when they host former Titans quarterback Ryan Fitzpatrick and the Texans (3-4).
After dropping four straight, the Titans edged previously winless Jacksonville 16-14, then lost to Washington last week.
Whitehurst was 17 of 26 for 160 yards, two touchdowns and an interception in the 19-17 defeat to the Redskins.
Information from ESPN.com's Paul Kuharsky and STATS LLC was used in this report.