Lee County, which encompasses Fort Myers, accounts for most of the fatalities.
The remnants of Ian are charging up the East Coast on Saturday after making landfall as a Category 1 hurricane in South Carolina on Friday afternoon.
The monster storm made its first U.S. landfall on Wednesday on Florida's west coast as a powerful Category 4 hurricane, shredding homes with ferocious winds topping 150 mph. Florida's death toll has climbed to at least 81, according to information from local officials.
Hurricane Ian is barreling toward Florida, and satellite images show the eye of the storm packed with lightning as it strengthens over the Gulf of Mexico.
The storm is currently forecast to make landfall on Florida's western coast on Wednesday between 1 and 6 p.m., somewhere between Port Charlotte and Sarasota.
See the latest maps and read more about Hurricane Ian's projections and possible paths here.
Florida Gov. Ron DeSantis has urged Floridians to take Hurricane Ian seriously as the powerful storm heads to the state.
"You don't get a mulligan when your personal safety is at risk,” he said during a press conference on Tuesday.
About 2.5 million people in the state are under evacuation orders.
"This thing is the real deal. It is a major, major storm,” DeSantis said.
-ABC News’ Darren Reynolds
Florida Gov. Ron DeSantis has activated 5,000 Florida National Guardsmen to armories across the state in preparation for Hurricane Ian, which is forecast to hit the state on Wednesday.
Roughly 2,000 National Guard members from neighboring states such as Tennessee are also being activated to assist, the Florida National Guard said in a statement Tuesday.
"The Florida National Guard is well-equipped, with assets including high-wheeled vehicles, helicopters, boats, generators and more," the statement said.
The U.S. Navy has authorized non-essential personnel in various Florida counties to evacuate.
-ABC News’ Matt Seyler
Hurricane Ian, barreling north toward Florida with 120 mph winds, is now located about 230 miles away from Sarasota.
Ian is expected to make landfall in Florida on Wednesday afternoon or early evening.
Ian's outer bands are already hitting South Florida, bringing a threat of heavy downpours, strong wind gusts, frequent lightning and even tornadoes. A tornado watch is in effect for South Florida until 5 a.m. Wednesday.
-ABC News’ Dan Peck
