Hurricane Milton updates: 16 dead across Florida in storm's aftermath

Hurricane Milton was a Category 5 hurricane with maximum sustained winds close to 160 mph as of 1 a.m. ET Wednesday, according to the National Hurricane Center's latest update. The storm is in the Gulf of Mexico moving northeast towards Florida at around 12 mph.

The storm is expected to make landfall along Florida's west-central coast as a Category 3 storm late Wednesday or early Thursday, subsequently moving off the east coast of Florida and into the Atlantic Ocean on Thursday afternoon.

"Milton is expected to be a dangerous major hurricane when it reaches the west-central coast of Florida," the NHC said early Wednesday. "Weather conditions are expected to begin deteriorating this afternoon."

Hurricane-force winds extend outward from Milton's center to around 30 miles, with tropical-storm-force extending out to 140 miles.

Officials in St. Petersburg issued a public safety advisory Tuesday for residents and businesses near tower cranes ahead of Hurricane Milton making landfall in Florida.

Due to anticipated wind gusts from the storm exceeding 100 mph, the high winds could potentially exceed the safe operational limits for tower cranes and pose a risk of malfunction, the city said in a press release.

"Lowering or securing a tower crane is scheduled weeks in advance and is not a feasible option within the timeframe of an approaching storm due to the rapid intensification and forecasted path," the city said.

The four construction sites of "particular concern" are 400 Central Ave. (downtown), 275 1st Ave. S (downtown) 1000 1st Ave. N (downtown) and 101 Main St. N (Carillon), according to the city.

Ahead of Hurricane Milton's impact, the mayor of Bradenton, Florida, joined ABC News Live Tuesday to issue a grave warning to residents who are not planning to evacuate.

"Get out of these areas because we can replace your home, we can't replace your life," Mayor Gene Brown said. "And we don't want to be finding bodies floating in rivers -- and we've seen that before," he added.

Bradenton lies on the west coast of Florida, sitting in the middle of the forecast path for Hurricane Milton, which is forecast to make landfall between Wednesday night and Thursday morning.

Brown added that a local sheriff is advising those who do not evacuate to "Write your name on your arm so we can identify you. We're all talking the same way," Brown said.

Jacksonville Mayor Donna Deegan urged residents to prepare for Hurricane Milton's impact in a press conference Tuesday.

Deegan asked residents to "batten down the hatches" and hunker down until conditions improve.

"We are expecting river flooding at the height of the storm, with peak tides carrying into Thursday evening," said Deegan. "We're asking everyone to stay off the roads. If you haven't already decided where you'll shelter, please do so now and stay there."

-ABC News' Jason Volack