The Rev. Al Sharpton told mourners that the body camera video “speaks for itself.”

“We understand that there are concerns about public safety. But you don’t fight crime by becoming criminals yourself,” Sharpton said.

He vowed, “We won’t stop until we hold you accountable and change this system.”

Sharpton said he wants to see the George Floyd Justice in Policing Act passed so “you have to think twice before you beat Tyre Nichols. You think twice before you shoot at someone unarmed.”

He added, "If that man had been white, you wouldn't have beat him. ... We're asking to be treated equal."

Sharpton, who was raised by a single mother, said he was "touched" when he heard Tyre Nichols calling for his mother on the video, "just like George Floyd was calling for his mother."

"All he wanted to do was get home."

3:50

Sharpton delivers eulogy at Tyre Nichols’ funeral

The Rev. Al Sharpton vowed “we won’t stop until we hold you accountable and change this system.”

Vice President Kamala Harris said to Tyre Nichols’ mother and stepfather, “You have been extraordinary in terms of your strength, your courage and your grace.”

“Mothers around the world, when their babies are born, pray to God when they hold that child, that that body and that life will be safe,” Harris said. “Yet we have a mother and a father who mourn the life of a young man who should be here today. They have a grandson who now does not have a father.”

Nichols died in an "act of violence at the hands and the feet of the people who have been charged with keeping them safe," she said. "This violent act was not in pursuit of public safety."

She said passing The George Floyd Justice in Policing Act is "non-negotiable."

4:08

VP Harris speaks at Tyre Nichols’ funeral

“Tyre Nichols should have been safe,” Vice President Kamala Harris said at the service.

Families of other Black Americans killed by police -- George Floyd, Breonna Taylor, Eric Garner and Botham Jean -- came to pay their respects at Wednesday’s funeral.

“They’ve come to be with you on this day from all over the country,” the Rev. Al Sharpton said.

Vice President Kamala Harris had a long embrace with Tyre Nichols’ mother, RowVaughn Wells, when she arrived at the service.

Harris is sitting next to Wells in the front pew.

-ABC News' Steph Wash