Tambor Felt Great 'Responsibility' to Transgender Community in 'Transparent'

"Lives are at stake," the "Transparent" star says.

— -- Actor Jeffrey Tambor said that that when he first read the script for "Transparent," he was so excited about the possibilities he told creator Jill Soloway "I'm in 50,000 times," he told ABC News.

He continued, "lives are at stake."

"What Jill Soloway [the show's creator] did was shoot this arrow into the zeitgeist, the revolution was already there," he told ABC News. "I just think the timing was amazing and momentous."

Tambor said he's seen a change in how people perceive the transgender community and even approach him as the show is enters its fourth season.

He told a story of a man "from the other side of the spectrum," approaching him in public. He believed something nefarious might happen, buy instead, "he just put his hand in mine and said 'Thank you for teaching me about something I didn't know.' That's the whole thing."

The man wasn't the only person who's treated the acclaimed actor differently.

"When I started this I would get the odd comment or odd tweet that was less than salutary," he said. "That doesn't happen anymore. I'm so grateful ... I'm more aware as a citizen, as a husband, as a guest, as a parent if you will. It woke me up and I think everyone is waking up."