On average, approximately 12,200 Americans are being admitted to the hospital each day with COVID-19. The forecast models used by the CDC suggest that by Sept. 27, that number could surge to as high as 22,400 a day.

The lower end of the forecast puts the daily hospital admissions at around 6,400.

There are signs the rate of hospital admission nationwide may be slowing, with the U.S. Centers for Disease Control and Prevention reporting hospital admissions will likely "remain stable or have an uncertain trend over the next 4 weeks."

Kentucky currently tops the list of states expected to see the most hospital admissions, per capita, in the next two weeks, followed by Florida and Georgia.

-ABC News' Arielle Mitropoulous

The American Medical Association, American Pharmacists Association and American Society of Health-System Pharmacists are calling for an "immediate end" to prescribing, dispensing or using the deworminig drug ivermectin to treat or prevent COVID-19.

Ivermectin is available in different formulations for both people and animals to treat parasites. It is not approved to treat or prevent COVID-19, nor is there enough evidence to support its use. Though amid a surge in COVID-19 cases in the U.S., internal data from the Centers for Disease Control and Prevention reviewed by ABC News estimates a 19-fold increase of the medicine being distributed during the first week of August, alongside an increase in reported cases of illness related to ivermectin toxicity.

The prescribing and dispensing of ivermectin has increased 24-fold since before the pandemic, according to the medical and pharmaceutical associations, which said in a joint statement they were "alarmed" by an exponential increase in recent months as well.

"[We] are urging physicians, pharmacists, and other prescribers -- trusted healthcare professionals in their communities -- to warn patients against the use of ivermectin outside of FDA-approved indications and guidance, whether intended for use in humans or animals, as well as purchasing ivermectin from online stores," the associations said. "Veterinary forms of this medication are highly concentrated for large animals and pose a significant toxicity risk for humans."

-ABC News' Sony Salzman

Moderna has submitted initial data to the U.S. Food and Drug Administration on its vaccine booster, the pharmaceutical company announced Wednesday.

Its booster candidate would be half the dose (50 micrograms) of the original dosing (two shots of 100 micrograms each).

Federal officials have said they hope to begin administering booster shots for many Americans starting on Sept. 20, with the third shot at least eight months after the second.

The FDA has only authorized booster shots of Pfizer's and Moderna's COVID-19 vaccines for people who are immunocompromised. The Centers for Disease Control and Prevention's independent advisory board also recommended booster shots for those with weakened immune systems.

Pfizer is also seeking authorization for a third dose of its COVID-19 vaccine. The FDA announced Wednesday it will hold a public meeting of its independent advisory committee on Sept. 17 to discuss the application.

-ABC News' Eric Strauss

Even with the delta variant, schools are still safe for children if guidelines are followed, CDC Director Rochelle Walensky said Wednesday at a town hall with the National Parent Teacher Association.

For the most part, Walensky said, "there's more disease happening outside of school than there is happening within a school."

Walensky, a mother of three, said she understands why parents are anxious.

But she added, "What we do know is when we implement the guidance for safe schools -- we implement the masking, the ventilation strategies, the cohorting and the screening strategies -- that we can have our kids be safe."

American Academy of Pediatrics President Dr. Lee Beers said at the town hall that it's still a very small percentage of children who get severely sick. The U.S. saw 200,000 cases among kids in the last week with about 2,000 of them hospitalized, Beers said.

-ABC News' Cheyenne Haslett

Florida Gov. Ron DeSantis filed an appeal against a court ruling invalidating his ban on student mask mandates Thursday evening.

The governor had banned school districts from implementing mask mandates without a parent opt-out.

The move unleashed a stay of proceedings that enables the state to continue punishing districts, at least until Wednesday, when a judge will decide whether to vacate the stay.

In the meantime, school board members across the state could continue to lose their salaries if their schools set mask mandates -- a punishment given to board members in two counties and threatened to those in eight others.

The appeal comes a week after Judge John C. Cooper found that a blanket ban on face masks in schools "does not meet constitutional muster.”

-ABC News' Will McDuffie