"Mrs. Doubtfire the Musical" has becomes the latest Broadway show to announce it is pausing performances amid the rapidly rising number of COVID-19 cases in New York City.

In a post shared on Twitter, producers announced the musical will "be taking a hiatus" between Jan. 10 and March 14.

Anyone with tickets for performances during the hiatus can either exchange for performances after March 15 or request a refund.

Puerto Rico's COVID-19 positivity rate spiked to 33% on Monday, according to the island’s health department COVID dashboard.

This is a 16-fold jump from the 2% positivity rate reported just two weeks ago, which was a record low.

Scientist Mónica Feliú-Mójer from Ciencia PR, an organization that focuses on scientific education in Puerto Rico, said the rapid increase is due to many factors, including people's behavior.

She said people gathering over the holidays, while a highly transmissible variant continued to spread, led to the spike in the positivity rate.

“The holidays are culturally very, very important and everyone thought this would be a different Christmas. People were eager to get together,” Feliú-Mójer told ABC News.

Read more here.

-ABC News' Cristina Corujo

South Korea on Monday reported the deaths of two patients in their 90s who tested positive for omicron.

Both were receiving treatment in Gwangju, about 200 miles south of Seoul, the semi-official Yonhap News Agency said.

South Korean health officials reported 111 new omicron cases on Monday, bringing its total to 1,318 omicron cases.

About 83% of South Korea's population has been fully vaccinated, according to the Korea Disease Control and Prevention Agency. About 36% received a booster.

Israel's Ministry of Health approved a fourth dose of COVID-19 vaccine for health care workers and people over 60 years old, Prime Minister Naftali Bennett said.

"Israel will once again be pioneering the global vaccination effort," Bennett said at a press conference in Jerusalem. "Omicron is not Delta -- it’s a different ball-game altogether."

Fourth doses will be administered four months after booster shots, Bennett said.

ABC News' Jordana Miller

The American Medical Association, the nation’s largest association of physicians, has criticized the Centers for Disease Control and Prevention's new quarantine and isolation guidance for COVID-19, saying the recommendations "are risking further spread of the virus."

The CDC updated its guidelines on Dec. 27, saying asymptomatic people who test positive for COVID-19 should self-isolate for five days rather than 10.

"The American people should be able to count on the Centers for Disease Control and Prevention (CDC) for timely, accurate, clear guidance to protect themselves, their loved ones, and their communities. Instead, the new recommendations on quarantine and isolation are not only confusing, but are risking further spread of the virus," the American Medical Association's president, Dr. Gerald E. Harmon, said in a statement Wednesday night.

Harmon referenced data cited by the CDC in its rationale for shortening the isolation period, which estimates 31% of people remain infectious five days after a positive COVID-19 test, suggesting that data proves thousands of Americans could return to their lives while still infected.

"With hundreds of thousands of new cases daily and more than a million positive reported cases on January 3, tens of thousands -- potentially hundreds of thousands of people -- could return to work and school infectious if they follow the CDC’s new guidance on ending isolation after five days without a negative test," Harmon said. "Physicians are concerned that these recommendations put our patients at risk and could further overwhelm our health care system."

Harmon said a negative COVID-19 test should be required for ending isolation after a positive test, as reentering society without knowing whether an individual is still positive ultimately risks further transmission of the virus.

Although test availability remains an issue nationwide, Harmon also called on the Biden administration to ramp up production and distribution of tests, adding that "a dearth of tests at the moment does not justify omitting a testing requirement to exit a now shortened isolation."

-ABC News' Arielle Mitropoulos