Los Angeles County Health Director Barbara Ferrer broke down as she revealed the latest tallies of coronavirus cases and deaths Wednesday.

There were 9,243 new cases and 75 new deaths recorded Wednesday, according to the health department. The county has seen 475,271 total cases and 8,075 total deaths during the pandemic.

"The more terrible truth is that over 8,000 people who were beloved members of their families are not coming back and their deaths are an incalculable loss to their friends and their family, as well as our community," Ferrer said while breaking down in tears.

Roughly 3,200 people currently hospitalized with COVID-19 in Los Angeles, 23% of whom are in the intensive care unit and 15% on ventilators, according to the health department.

"Given that we are just now seeing the hospitalizations from the Thanksgiving holiday, we anticipate that the number will continue to grow over the next few weeks with potentially 700 new daily COVID hospitalizations in just one week from now," Dr. Christina Ghaly, director of the LA County Health Services Department, said.

-ABC News' Cammeron Parrish

The Big Ten Conference Administrators Council voted Wednesday to eliminate the game minimum requirement for teams to play in the conference championship, clearing the way for Ohio State to play for the title despite only playing five games this season due to COVID-19 cancellations.

Among the cancellations was this weekend's game against University of Michigan after Michigan reported "an increasing number of positive COVID-19 cases and student-athletes in quarantine."

The conference said, "The decision was based on a competitive analysis which determined that Ohio State would have advanced to the Big Ten Football Championship Game based on its undefeated record and head-to-head victory over Indiana regardless of a win or loss against Michigan."

Ohio State will play Northwestern in the Big Ten Football Championship Game.

The conference had voted prior to the season that a team must played at least six games to qualify for the title game.

California recorded 30,851 new cases on Tuesday, bringing the state's case total to over 1.42 million.

The Golden State's seven-day positivity rate stands at 10%.

California Gov. Gavin Newsom has ordered regions to follow a stay-at-home order if their intensive care unit capacity falls below 15%.

The San Joaquin Valley and Southern California regions have already met this criteria and are under stay-at-home orders until at least Dec. 28.

The Greater Sacramento region now meets the criteria and a stay-at-home order will go into effect there the night of Dec. 10.

Northern California and the Bay Area are the two remaining regions with ICU capacities above 15%.

Once the FDA approves the Pfizer/BioNTech vaccine, 2.9 million doses will go out immediately in the U.S., said Gen. Gus Perna, commander of the Army Materiel Command. The second batch of 2.9 million will be close behind, within 21 days, Perna said.

Twenty million Americans are expected to be vaccinated by the end of 2020, Health and Human Services Secretary Alex Azar said.

"We remain confident that across our portfolio of multiple vaccines, we will have enough doses for any American who wants a vaccine by the end of the second quarter of 2021," Azar said.

After two allergic reactions to the Pfizer/BioNTechvaccine were reported in the United Kingdom, Moncef Slaoui, Trump’s chief scientific adviser on vaccines, told reporters, "The expectation would be that subjects with known severe reaction, allergic reaction, should not take the vaccine, until we understand exactly what happened here."

ABC News' Anne Flaherty contributed to this report.

U.S. President-elect Joe Biden on Monday announced key nominations and appointments of his health team, a slate of experts and public officials who will lead his administration's response to the coronavirus pandemic.

"This trusted and accomplished team of leaders will bring the highest level of integrity, scientific rigor and crisis-management experience to one of the toughest challenges America has ever faced -- getting the pandemic under control so that the American people can get back to work, back to their lives and back to their loved ones," Biden said in a statement. "This team of world-class medical experts and public servants will be ready on day one to mobilize every resource of the federal government to expand testing and masking, oversee the safe, equitable and free distribution of treatments and vaccines, reopen schools and businesses safely, lower prescription drug and other health costs and expand affordable health care to all Americans, and rally the country and restore the belief that there is nothing beyond America's capacity if we do it together."

California Attorney General Xavier Beccera is nominated to serve as the Secretary of Health and Human Services.

Dr. Vivek Muthy, a physician and research scientist, is nominated to be the Surgeon General, a role he served during the Obama administration.

Dr. Rochelle Walensky, an expert on virus testing, prevention and treatment, is nominated to serve as director of the Centers for Disease Control and Prevention.

Dr. Marcella Nunez-Smith, an expert on health care disparities, will serve as the COVID-19 Equity Task Force Chair.

As Biden said last week, Dr. Anthony Fauci will stay on in his current role as director of the National Institute of Allergy and Infectious Diseases. Fauci will also serve as Biden's chief medical adviser on COVID-19.

Jeff Zients, co-chair of Biden's transition team who led the Obama administration's National Economic Council, will serve as coordinator of the COVID-19 Response as well as counselor to the president.

Natalie Quillian, a national security expert, will serve as deputy coordinator of the COVID-19 response.

ABC News' John Verhovek contributed to this report.