The last week marks the deadliest week for the U.S. since the beginning of the pandemic, with 15,578 deaths -- roughly equivalent to 92 deaths reported every hour.

The U.S. is now averaging more than 200,000 new cases each day -- three times higher than the country's summer peak in July, and more than six times higher than the country's spring peak in April.

There has not been a single day with less than 100,000 daily cases for the last five straight weeks, according to an ABC News analysis of data compiled by the COVID Tracking Project.

In the last week alone, the U.S. has reported 1.4 million new COVID-19 cases, more than any other week on record, and equivalent to 1 in every 231 Americans testing positive.

With numerous days now over the 200,000 mark, the seven-day average of new coronavirus cases has increased by 87% in the last month.

ABC News' Arielle Mitropoulos contributed to this report.

Pennsylvania Gov. Tom Wolf said he tested positive for COVID-19 on Tuesday and is isolating at home.

"I have no symptoms and am feeling well," Wolf said in a statement. “I am continuing to serve the commonwealth and performing all of my duties remotely."

Wolf's wife has been tested and is awaiting results.

A record 590 new fatalities were reported in Germany on Wednesday, beating the record previously set Tuesday of 568 new deaths, the Robert Koch-Institute reported.

Germany has now lost 19,932 lives to COVID-19.

"A reversal of this trend so far is not in sight," German Deputy Government spokesperson Martina Fietz said, adding that in some regions, hospitals are reaching their limits.

"With more than 4,200 people in intensive care, the number is considerably higher than in the spring," Fietz said.

Chancellor Angela Merkel spoke in parliament Wednesday, pleading with regional leaders to enforce tighter regulations to stop the spread.

Over 1.2 million people in Germany have been diagnosed.

ABC News' Christine Theodorou contributed to this report.

Canada has authorized the Pfizer vaccine, becoming the third country to do so after the United Kingdom and Bahrain.

Canada's health department said, "after a thorough, independent review of the evidence, Health Canada has determined that the Pfizer-BioNTech vaccine meets the Department's stringent safety, efficacy and quality requirements for use in Canada."

A rollout date was not announced. Initial supplies will be limited with more doses available in the spring, officials said.

Health Canada is also reviewing another three vaccines.

ABC News' Kirit Radia and Christine Theodorou contributed to this report.

U.S. President-elect Joe Biden on Monday announced key nominations and appointments of his health team, a slate of experts and public officials who will lead his administration's response to the coronavirus pandemic.

"This trusted and accomplished team of leaders will bring the highest level of integrity, scientific rigor and crisis-management experience to one of the toughest challenges America has ever faced -- getting the pandemic under control so that the American people can get back to work, back to their lives and back to their loved ones," Biden said in a statement. "This team of world-class medical experts and public servants will be ready on day one to mobilize every resource of the federal government to expand testing and masking, oversee the safe, equitable and free distribution of treatments and vaccines, reopen schools and businesses safely, lower prescription drug and other health costs and expand affordable health care to all Americans, and rally the country and restore the belief that there is nothing beyond America's capacity if we do it together."

California Attorney General Xavier Beccera is nominated to serve as the Secretary of Health and Human Services.

Dr. Vivek Muthy, a physician and research scientist, is nominated to be the Surgeon General, a role he served during the Obama administration.

Dr. Rochelle Walensky, an expert on virus testing, prevention and treatment, is nominated to serve as director of the Centers for Disease Control and Prevention.

Dr. Marcella Nunez-Smith, an expert on health care disparities, will serve as the COVID-19 Equity Task Force Chair.

As Biden said last week, Dr. Anthony Fauci will stay on in his current role as director of the National Institute of Allergy and Infectious Diseases. Fauci will also serve as Biden's chief medical adviser on COVID-19.

Jeff Zients, co-chair of Biden's transition team who led the Obama administration's National Economic Council, will serve as coordinator of the COVID-19 Response as well as counselor to the president.

Natalie Quillian, a national security expert, will serve as deputy coordinator of the COVID-19 response.

ABC News' John Verhovek contributed to this report.