COVID-19 updates: Michigan, Minnesota, New Mexico leading nation in cases

Michigan has the highest infection rate, followed by Minnesota and New Mexico.

As the COVID-19 pandemic has swept the globe, more than 5.1 million people have died from the disease worldwide, including over 771,000 Americans, according to real-time data compiled by Johns Hopkins University's Center for Systems Science and Engineering.

Just 69% of Americans ages 12 and up are fully vaccinated against COVID-19, according to data from the U.S. Centers for Disease Control and Prevention.


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DC to lift indoor mask mandate on Monday, masks still required in White House

Washington, D.C., will lift its indoor mask mandate on Monday.

"Instead of following a blanket mandate, residents, visitors, and workers will be advised to follow risk-based guidance from DC Health that accounts for current health metrics and a person’s vaccination status," Mayor Muriel Bowser's office said in a statement

Private businesses can still require masks.

Masks will still be required in places including public transportation, schools, child care facilities and nursing homes.

The White House will still require masks indoors, a White House spokesman said, because D.C. has a "substantial" level of community transmission, according to the CDC.

"The White House follows CDC guidance which recommends masking in areas of high or substantial transmission," the spokesman, Kevin Munoz, told ABC News.-ABC News' Beatrice Peterson, Ben Gittleson


American Academy of Pediatrics updates guidance for testing in kids

The American Academy of Pediatrics has updated its testing guidance for children, aligning its recommendations with the CDC's for fully vaccinated individuals.

AAP now recommends that fully vaccinated people, who were in close contact with someone with COVID-19, should be tested five to seven days after the exposure. It is recommended that individuals who are not fully vaccinated be tested immediately after they learn of exposure. If they test negative, they should be tested again five to seven days after their last exposure, or immediately after symptoms develop.

The CDC already recommended that vaccinated people get tested five to seven days after exposure.

-ABC News' Arielle Mitropoulos, Sony Salzman


FDA may issue guidance on boosters for adults as soon as this week

The CDC’s Advisory Committee on Immunization Practices will meet on Friday to discuss expanding booster eligibility for the Pfizer vaccine.

A government official confirmed to ABC News that the FDA may issue guidance on Pfizer and Moderna boosters for adults as soon as this week.

According to federal guidelines, boosters are currently available for: adults who received the Johnson & Johnson shot at least two months ago; Moderna/Pfizer recipients who are 65 and older and six months out from their second dose; and adult Moderna/Pfizer recipients who are six months out from the second dose and at higher risk because of a comorbidity, living or work environment.

But booster eligibility has already been expanded in some states this week, including New York and Arkansas.

-ABC News' Eric M. Strauss


Pfizer asks FDA for COVID-19 pill authorization

Pfizer has asked the Food and Drug Administration to authorize its COVID-19 pill, the company announced in a press release Tuesday.

Both Merck and Pfizer are working on pills that appear very effective at keeping patients out of the hospital, according to the companies.

The Merck medication could be FDA authorized, recommended and available by the end of the year. The FDA's advisory committee is slated to discuss the Merck application on Nov. 30.

Authorization for Pfizer is not expected until early next year.

-ABC News' Sony Salzman


Consider rapid testing before Thanksgiving, experts say

Former Baltimore health commissioner Dr. Leana Wen said in an interview Monday hosted by the Bipartisan Policy Center that her family is rapid-testing on Thanksgiving because they're gathering indoors with multiple families and have young, unvaccinated children.

She said it was reasonable for families with immunocompromised members to continue to take precautions, like rapid test and gather outdoors.

"A family in which everybody is generally healthy and fully vaccinated might take very different types of risks than a family with unvaccinated young kids or elderly, immunocompromised family members," she said.

Dr. Jerome Adams, former Surgeon General under President Donald Trump, said to make sure all relatives are vaccinated and that no one has cold symptoms.

"Even if you're vaccinated, if you're coughing, if you're sneezing, if you've got symptoms, you still could be spreading the virus," he said.

Looking to the future, Dr. Anthony Fauci said, "If we can get most of the people who are eligible to be boosted, boostered, we can go a long way to make in 2022 much more of a normal year than what we've seen in 2021."

-ABC News' Cheyenne Haslett