An adult in South Carolina’s Lowcountry region has become the state’s first confirmed case of the United Kingdom COVID-19 variant, South Carolina’s Department of Health and Environmental Control said.

The person "has an international travel history," the department said.

The U.S. has confirmed at least 434 cases of the B.1.1.7 U.K. variant across 30 states, South Carolina officials said.

"Experts agree that existing vaccines work to protect us from this variant, even if we don’t know just how effective they are," the South Carolina officials said. "At this time, there’s no conclusive evidence to prove that the B.1.1.7 variant causes more severe illness."

ABC News’ Josh Hoyos contributed to this report.

The Coachella Valley Music and Arts and Stagecoach Country Music festivals, set for April, were canceled on Friday by Dr. Cameron Kaiser, health officer for Riverside County, California.

Riverside County’s positivity rate stands at 20%. The county has 0% bed availability in its intensive care units.

January has been the deadliest month since the pandemic began, with 90,844 total deaths, according to data compiled by Johns Hopkins University.

The U.S. coronavirus death toll stands at 436,810 -- with the Center for Disease Control and Prevention projecting that more than 77,000 deaths could be reported by Feb. 20.

California is now the second U.S. state with known detection of the Brazil P.1 variant.

Minnesota health officials confirmed earlier this week the nation's first known COVID-19 case associated with the variant.

Inside Stanford's Clinical Virology Laboratory, Dr. Benjamin Pinsky and his team found two strains of the virus: the Brazil strain and the U.K. strain, KGO reported Saturday morning.

"It's in about 17% of the samples that we've sequenced," Pinsky told KGO.

Forty people in Gambia who tested positive for COVID-19 over the past week have refused to self-isolate or have escaped treatment centers, according to the country's health ministry, which vowed to reveal the identities of those flouting public health regulations.

Officials are also aware of a "large number of travelers who recently arrived" in the small West African nation from countries considered COVID-19 hotspots and "have refused to abide to official protocols and/or report to the health authorities for the mandatory test upon arrival," said Modou Njai, director of health promotion and education at Gambia's Ministry of Health.

"The Ministry continues to treat these matters with utmost and grave concern and thus, the Ministry is hereby giving an order and ultimatum to all those concerned, that they are required to report themselves to the health authorities with immediate effect and failure of which will lead to serious consequences, including the publication of names and identifying information of all those at large," Njai said in a statement Tuesday.

"The Ministry would like to stress that this serious and ruthless misconduct will no longer be condoned under any circumstances," he added. "Anyone found not willing to cooperate with COVID-19 regulations will have their names and identifying information published on the media and thereafter, drastic measures will be taken against anyone that is non-compliant."

Gambia, home to some 2.3 million people, has confirmed 4,008 cases of COVID-19 since the start of the pandemic, including at least 128 deaths, according to the latest data from the health ministry.