The closure of the Canada-U.S. border has been extended to Feb. 21.

The border has been closed to all nonessential traffic since March. The closure agreement is reviewed by U.S. and Canadian government authorities each month.

ABC News’ Christine Theodorou contributed to this report.

U.S. Health and Human Services Secretary Alex Azar said the federal government will no longer hold back COVID-19 vaccine doses and is now recommending states inoculate anyone 65 and older as well as those under the age of 65 who have two or more conditions or illnesses.

"This is just a staging and moving to the next phase on the vaccine program. We've had so much success with quality and predictable manufacturing and almost flawless distribution of the vaccine, but we have seen now that the administration in the states has been too narrowly focused," Azar told ABC News chief anchor George Stephanopoulos in an interview Tuesday on Good Morning America.

"So, what are we doing? Three things. First, We have already made available every dose of vaccine," he said. "So we had been holding back second doses as a safety stock. We now believe that our manufacturing is predictable enough that we can ensure second doses are available for people from ongoing production. So everything is now available to our states and our health care providers."

"Second, we are calling on our governors to now vaccinate people age 65 and over and under age 65 with a comorbidity, because we have got to expand the group," he continued. "We've already distributed more vaccine than we have health care workers and people in nursing homes."

"Third, we've got to get more channels of administration," he added. "We've got to get it to pharmacies, get it to community health centers, and we are here and we will deploy teams to support states doing mass vaccination efforts if they wish to do so. It has been overly hospitalized so far in too many states."

As of 9 a.m. ET on Monday, more than 25 million COVID-19 vaccine doses have been distributed nationwide but fewer than 9 million people have received their first dose, according to data provided by the U.S. Centers for Disease Control and Prevention.

The European Medicines Agency (EMA) said Tuesday that it has received an application for conditional marketing authorization for the COVID-19 vaccine developed by England's University of Oxford and British-Swedish pharmaceutical giant AstraZeneca.

Conditional marketing authorization is the process used to speed up the approval of treatments and vaccines amid public health emergencies. The EMA said the assessment of the Oxford/AstraZeneca vaccine "will proceed under an accelerated timeline," and that an opinion on whether to issue an authorization could be announced by Jan. 29.

"If EMA concludes that the benefits of the vaccine outweigh its risks in protecting against COVID‑19, it will recommend granting a conditional marketing authorisation," the agency said in a statement Tuesday. "The European Commission will then fast-track its decision-making process with a view to granting a conditional marketing authorisation valid in all EU and EEA Member States within days."

Russia has extended its suspension of air travel with the United Kingdom through Feb. 1 amid growing concerns over a new, more contagious variant of the novel coronavirus.

"For the purpose of protecting public health, the restrictions have been extended through 11:59 p.m. on February 1, 2021," Russia's coronavirus response headquarters said in a statement Tuesday.

The ban was first imposed in late December.

The move comes after Russia confirmed its first cases of a new, highly infectious strain that is thought to have emerged in England late last year. The variant, called B117, is currently prevalent in London and other parts of southeastern England, and has since spread to more than a dozen other countries.

With more than 3.3 million confirmed cases of COVID-19, Russia has the fourth-highest tally of diagnosed infections in the world, followed by the U.K., according to a real-time count kept by Johns Hopkins University.

Russia's coronavirus response headquarters confirmed 22,934 new cases and 531 additional deaths from the disease on Monday, bringing the cumulative total to 3,448,203 cases with 62,804 deaths.

ABC News' Tanya Stukalova contributed to this report.

Japanese Prime Minister Yoshihide Suga declared a state of emergency in seven additional areas on Wednesday, as COVID-19 cases continued to climb.

The latest state of emergency was declared for the prefectures of Osaka, Hyogo, Kyoto, Aichi, Gifu, Fukuoka, and Tochigi.

The move comes one week after Suga declared a state of emergency in Tokyo and three neighboring prefectures due to rising infections and a growing death toll.

A state of emergency declaration gives the governors of those respective regions the authority to ask residents for cooperation in efforts to curb the spread of the virus. There are currently no legal ramifications for non-compliance.

Under the state of emergency, which takes immediate effect and is expected to end Feb. 7 for all 11 prefectures, Suga said governors will ask residents to refrain from dining out and to stay home after 8 p.m. unless for essential reasons. They will also ask companies to decrease the number of employees commuting to work by 70%.

Suga said bars and restaurants will be asked to stop serving alcohol by 7 p.m. and to close by 8 p.m. Governors may disclose the name of the businesses that don't comply, while those that do will be given 1.8 million Japanese yen ($17,000) per month.

Spectator events will be limited to an audience of 5,000 people. Schools will not be asked to close, according to Suga.

Suga's predecessor, Shinzo Abe, declared a nationwide state of emergency relatively early in the pandemic in April, which lasted for a month. At that time, residents were asked to reduce person-to-person contact by 80% and to practice "jishuku," or "self-restraint," by staying at home and closing non-essential businesses.

The Japanese Ministry of Health, Labor and Welfare registered 4,521 newly confirmed cases of COVID-19 as well as 51 additional deaths from the disease on Tuesday, bringing the country's cumulative total to 295,257 cases with at least 4,144 deaths.

ABC News' Anthony Trotter contributed to this report.