The U.S. is now reporting nearly 118,000 new cases each day -- up by 45% in the last month, according to federal data.

Daily COVID-19-related hospital admissions have leapt by 46% in the last month.

Maine and New Hampshire are now averaging more new cases than at any other point in the pandemic, according to federal data.

New Hampshire currently holds the nation's highest case rate, followed by Rhode Island, Maine, Michigan, Wisconsin and Minnesota.

-ABC News' Arielle Mitropoulos

South Africa, one of the first countries to detect omicron, reported a record high of 26,976 new cases on Wednesday.

Just 26.09% of South Africa's residents are fully vaccinated, according to Africa CDC.

-ABC News' Christine Theodorou

George Washington University is joining Princeton, Cornell and NYU by canceling all events and moving exams online.

George Washington officials said there's "a significant increase" in cases, and while people are not severely sick, "it is critical that we act to limit the further spread."

-ABC News' Michelle Stoddart

Boston's historic baseball stadium Fenway Park, which transformed into a mass vaccination site last winter, is expected to reopen its doors as a booster shot location in January, Red Sox officials told ABC News.

The Red Sox are working with the city and the governor's office to finalize the plans, Red Sox spokeswoman Zineb Curran said.

-ABC News' Arielle Mitropoulos

A journalist traveling alongside U.S. Secretary of State Antony Blinken on his visit to Southeast Asia has tested positive for COVID-19 in Malaysia, according to U.S. Department of State spokesperson Ned Price.

Meanwhile, Blinken and his senior staff all tested negative for COVID-19 upon arrival in Kuala Lumpur on Tuesday night. The member of the traveling press pool who tested positive had last tested negative in Indonesia's capital, their previous stop, on Tuesday.

"The individual who tested positive will remain in isolation," Price said in a statement Wednesday, "and we will continue to adhere to and go beyond CDC guidance, including with our rigorous testing protocol, for the remaining traveling party."

Blinken has canceled a scheduled trip to Thailand "out of an abundance of caution" and will return home to the United States, according to Price.

"The Secretary expressed his deep regret to the Foreign Minister that he would not be able to visit Bangkok this week," Price said. "He explained that, in order to mitigate the risk of the spread of COVID-19 and to prioritize the health and safety of the U.S. traveling party and those they would otherwise come into contact with, the Secretary would be returning to Washington, D.C. out of an abundance of caution."

"The Secretary extended an invitation for the Foreign Minister to visit Washington, D.C. at the earliest opportunity and noted that he looked forward to traveling to Thailand as soon as possible," Price added. "They affirmed that they would use the upcoming engagements to further deepen the U.S.-Thai alliance."

The U.S. Embassy in Malaysia confirmed that the infected individual "was not involved and has not participated in any of Secretary Blinken's program in Kuala Lumpur."

"The sole member of the traveling party who tested positive is observing all requirements of the Ministry of Health," the embassy said in a statement Wednesday. "We confirm all other members of the party tested negative for COVID-19 upon arrival in Malaysia."

Blinken was in Indonesia on Tuesday, and the U.S. Embassy in Jakarta confirmed that no members of the traveling party tested positive for COVID-19.

All members of the U.S. delegation are required to be vaccinated against COVID-19 and undergo regular testing on trips.

-ABC News' Conor Finnegan