At least one person has died in the United Kingdom after being infected with the omicron variant, British Prime Minister Boris Johnson said Monday.

It's the first publicly confirmed death globally from the new variant of the novel coronavirus, which was initially identified in southern Africa last month and has since spread rapidly around the world. Deaths from omicron may have already occurred in other countries but no others have been publicly confirmed yet.

Speaking to reporters during a visit to a vaccination clinic in London, Johnson said the death was a patient who had been diagnosed at a hospital but gave no further details.

"Sadly, at least one patient has now been confirmed to have died with omicron," the prime minister said. "So I think the idea that this is somehow a milder version of the virus, I think that's something we need to set on one side and just recognize the sheer pace at which it accelerates through the population. So the best thing we can do is all get our boosters."

The National Football League will require that all its vaccinated Tier 1 and 2 employees receive COVID-19 booster shots by Dec. 27, according to a memo sent to all 32 teams within the professional American football league on Monday.

This group of employees includes coaches and other employees who work closely with NFL players and help in essential league operations.

"On November 29, the CDC issued a study showing that the effectiveness of the approved COVID-19 vaccines may decrease over time and has recommended that all eligible vaccinated individuals over the age of 18 should receive a booster shot," the memo states. "Given the increased prevalence of the virus in our communities, our experts have recommended that we implement the CDC’s recommendation."

The memo came as 36 players were added to the NFLS's COVID-19 reserve list. Players are currently not required to receive boosters; but in Monday’s memo, the NFL said teams should consider making boosters available for players and their families.

"Any individual who is not currently subject to the requirement for boosters will be required to obtain the booster within 14 days of becoming eligible," the memo states.

-ABC News’ Katie Conway

The U.S. Air Force gave administrative discharges to 27 personnel who refused to get vaccinated against COVID-19 and comply with the federal government's mandate.

Over 7,000 Air Force members are unvaccinated against COVID-19, which includes about 4,500 who are waiting to see if they are eligible for religious exemption. More than 1,500 religious exemption requests have been denied and those individuals remain unvaccinated.

The Air Force has not granted a single religious exemption, according to officials.

Over 1,000 members have outright refused to get their shots.

More discharges over vaccine refusal are likely, according to an official.

-ABC News' Luis Martinez

California is reinstating an indoor mask mandate from Dec. 15 to Jan. 15.

Half of the state is already under a mask mandate per local rules, according to California Health and Human Services Secretary Mark Ghaly.

California is also tightening restrictions on unvaccinated people at large events. At events with more than 1,000 people, anyone who isn’t vaccinated must show proof of a negative antigen test within 24 hours or a negative PCR test within 48 hours.

State officials also recommend that travelers get tested three to five days before arriving in California.

-ABC News' Matt Fuhrman

A journalist traveling alongside U.S. Secretary of State Antony Blinken on his visit to Southeast Asia has tested positive for COVID-19 in Malaysia, according to U.S. Department of State spokesperson Ned Price.

Meanwhile, Blinken and his senior staff all tested negative for COVID-19 upon arrival in Kuala Lumpur on Tuesday night. The member of the traveling press pool who tested positive had last tested negative in Indonesia's capital, their previous stop, on Tuesday.

"The individual who tested positive will remain in isolation," Price said in a statement Wednesday, "and we will continue to adhere to and go beyond CDC guidance, including with our rigorous testing protocol, for the remaining traveling party."

Blinken has canceled a scheduled trip to Thailand "out of an abundance of caution" and will return home to the United States, according to Price.

"The Secretary expressed his deep regret to the Foreign Minister that he would not be able to visit Bangkok this week," Price said. "He explained that, in order to mitigate the risk of the spread of COVID-19 and to prioritize the health and safety of the U.S. traveling party and those they would otherwise come into contact with, the Secretary would be returning to Washington, D.C. out of an abundance of caution."

"The Secretary extended an invitation for the Foreign Minister to visit Washington, D.C. at the earliest opportunity and noted that he looked forward to traveling to Thailand as soon as possible," Price added. "They affirmed that they would use the upcoming engagements to further deepen the U.S.-Thai alliance."

The U.S. Embassy in Malaysia confirmed that the infected individual "was not involved and has not participated in any of Secretary Blinken's program in Kuala Lumpur."

"The sole member of the traveling party who tested positive is observing all requirements of the Ministry of Health," the embassy said in a statement Wednesday. "We confirm all other members of the party tested negative for COVID-19 upon arrival in Malaysia."

Blinken was in Indonesia on Tuesday, and the U.S. Embassy in Jakarta confirmed that no members of the traveling party tested positive for COVID-19.

All members of the U.S. delegation are required to be vaccinated against COVID-19 and undergo regular testing on trips.

-ABC News' Conor Finnegan