Texas has become the second U.S. state to have a total of more than 2 million diagnosed cases of COVID-19.

The Lone Star state surpassed the grim milestone late Tuesday, with a cumulative tally of 2,014,645 confirmed cases. California currently has 2,795,978, according to a real-time count kept by Johns Hopkins University.

More people in the United States died of COVID-19 in the past week than they did from the flu during all of last season, data show.

There were an estimated 22,000 flu deaths nationwide during the 2019-2020 flu season, according to the U.S. Centers for Disease Control and Prevention. The flu season was regarded as moderate and stretched out over several months.

By contrast, there were 23,119 new COVID-19 deaths reported between Jan. 6-12, according to The COVID Tracking Project.

-ABC News' Anne Flaherty

There were 4,056 deaths due to COVID-19 reported on Tuesday in the U.S., according to The COVID Tracking Project.

That marks the second time new deaths surpassed 4,000, based on the tracker's tally, following the record 4,081 reported less than a week ago on Jan. 7.

The seven-day average number of deaths reported Tuesday also set a new record, the tracker said.

There were 213,885 new cases and 131,326 people are currently hospitalized due to the virus in the U.S.

Deaths from COVID-19 in the United Kingdom have jumped, as the country battles a new, more contagious variant of the novel coronavirus.

The U.K. reported 6,298 new COVID-19 deaths in the week ending Jan. 10, up from 4,165 the previous week, according to the World Health Organization's latest epidemiological report. There were 9.3 new deaths per 100,000 residents -- a 51% increase over the previous week, according to the WHO.

Elsewhere, the African region reported the highest percentage increases over any other region in cases and deaths during that time frame. There were over 174,000 new cases and over 4,300 new deaths, according to the report.

COVID-19 cases are on the decline in India, the second-most populous nation in the world. There were just over 126,000 new cases reported -- a 7% decrease in infections per 100,000 residents over the previous week, according to the report.

ABC News' Christine Theodorou contributed to this report.

Mississippi has allotted its entire supply of COVID-19 vaccines and doesn't expect more doses until mid-February, the state health department announced Wednesday.

"Neither the county health department drive-through sites, nor the [University of Mississippi Medical Center] vaccine scheduling website was designed to accommodate the monumental surge we are currently experiencing," the Mississippi State Department of Health said in a statement. "At this time, we have no additional vaccine, and every appointment is tied to an actual vaccination."

New appointments are expected to resume after an anticipated vaccine resupply in mid-February, the department said.

On Tuesday, the state opened vaccine eligibility to people ages 65 and older and those with certain chronic health conditions, which led to an influx of calls to the state's COVID-19 hotline, officials said. Previously, vaccinations were prioritized for health care workers, long-term care residents and those over the age of 75.

"We decided to open vaccines to many more people. We knew it would cause a rush, but believe it is more fair than having government arbitrarily limit access," Gov. Tate Reeves said on Twitter Wednesday evening.

As of Tuesday, the state had administered 62,744 vaccinations over the last four weeks, Reeves said during a press briefing.

ABC News' Will Gretsky contributed to this report.